ace à la propagation alarmante des bactéries résistantes aux antibiotiques, le développement de nouveaux antimicrobiens avec des modes d’action innovateurs est devenu une priorité mondiale. Parmi les différentes alternatives, les peptides antimicrobiens d’origine bactérienne comme les bactériocines sont très prometteurs. Ce projet s’intéresse particulièrement à cinq bactériocines produites par la bactérie Lacticaseibacillus paracasei qui ont […]

Cancer is associated with an accumulation of alterations in genes that confer the ability of cancer cells to grow uncontrollably. These alterations can contribute to increased deleterious function or loss of function of genes that normally regulate cell growth. Genes in our cells are organized on chromosomes which duplicate every time a cell divides. In […]

The evaluation at Northwood Care, using the ACHIEVE model, aims to determine what factors make employees efficient. This model assesses seven key elements: Ability, Clarity, Help, Incentive, Evaluation, Validity, and Environment. Managers use it to identify and address performance issues affecting employee efficiency. The evaluation is crucial because employees are a significant driver of organizational […]

Immunotoxins (ITs) are representing a subset of antibody drug conjugates where the synthetic toxin is replaced by a bacterial protein toxin. Major drawback is related to the immunogenicity of the protein not allowing repeated application. Consequently targeted human cytolytic fusion proteins (hCFPs) have been developed to replace the foreign protein toxin by a human apoptosis […]

Our collaborative project unites Brazilian and Canadian institutions to drive innovations in high-resolution microscopy and materials characterization. Leveraging cutting-edge techniques like High Harmonic Generation (HHG) and Terahertz (THz) sources, alongside novel imaging methods such as Spatial Frequency-modulated Imaging (SPIFI) and the Derivative Optical Imaging Technique (DOIT), the University of Federal do Paraná (UFPR) in Brazil […]

To ensure that PPPH priority projects are developed using the most up-to-date evidence and to increase the likelihood of project success, evidence synthesis will be crucial in facilitating a deeper understanding of community health issues, contributing factors, associated health inequities, and appropriate interventions to improve health outcomes. The objective of this project is to conduct […]

The proposed project is centered on developing an advanced technique known as Magnetic Resonance Navigation (MRN) for liver cancer treatment. This cutting-edge method employs the magnetic field of MRI machines to create micro-particle aggregates, which are then precisely directed to liver tumor-feeding arteries using magnetic field gradients. This approach promises to be less invasive and […]

In the context of an aging population, it is becoming more and more important to develop novel innovative kinds of sensors, able to detect early health changes that could potentially affect people’s health. Within this Globalink Research project, we intent to develop plasmonic based sensors, small, cheap and easy to deploy, which will be used […]

Lunanos Inc. and Ryerson University’s School of Graphic Communications Management are seeking to collaborate on a six-month project to develop an innovative colour-changing indicator label that will be used in healthcare facilities to track the cleaning of various equipment and surfaces to reduce the frequency of healthcare-associated infections (HAI). In Canada, 1 in 10 patients […]

This project aims to develop a novel therapeutic drug aimed at revolutionizing the treatment of severe cardiovascular diseases (CVD) and sepsis. Our project focuses on the modification of the ADAMTS13 protein, an enzyme that plays a crucial role in the blood clotting process. In patients with severe CVD or sepsis, ADAMTS13 is rapidly degraded, leading […]

Medventions is a full-time 14 week paid program that allows students and new graduates to take part in physician-led, hospital-based fellowship training. Fellows come from different areas of study and will get hands on experience in a clinical setting with innovators and experienced mentors. It equips fellows to identify priority healthcare needs and develop their […]

Les Streptocoques du groupe B (SGB) sont connus pour être l’une des principales causes de maladies infectieuses invasives chez les nouveau-nés en Amérique du Nord mais également à l’échelle mondiale. Le contrôle des infections à SGB repose sur une utilisation d’antimicrobiens dont l’efficacité n’est pas totalement satisfaisante tel que la pénicilline étant administré en première […]