Innovative Projects Realized

Explore thousands of successful projects resulting from collaboration between organizations and post-secondary talent.

30508 Completed Projects

2882
AB
5105
BC
825
MB
681
NL
860
SK
9051
ON
9491
QC
97
PE
586
NB
1141
NS

Projects by Category

High-throughput selection of monoclonal antibodies against GPCRs using a microfluidic single cell screening platform – Year two

Antibodies are biomolecules naturally produced by immune cells, called antibody-secreting cells, to protect against
infection and diseases. Each antibody-secreting cell makes a unique type of antibody that binds specifically to a target molecule. A major challenge in developing antibody therapeutics is selecting the most effective antibodies from the billions produced within any given host.
Our aim is to build on an established technology platform that uses analysis of very small volumes (1/10^9 liters) in
miniaturized devices (microfluidics) to select antibodies against challenging membrane receptor targets directly from
single cells. This project will advance new and innovative solutions to antibody drug discovery such as: finding
antibodies against difficult drug targets; improved capabilities in the selection of antibodies; and high-value
applications in vaccine development and improved approaches to immunotherapy. The work done in this project will
be directly transferable to AbCellera and bring important new capabilities to their technology platform.

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Faculty Supervisor:

T. Michael UnderHill

Student:

Partner:

AbCellera

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

The University of British Columbia

Program:

Elevate

Learning from Lax Kwil Ts’iit: Gitga’at Resource Use at Clamstown

Indigenous peoples on the northwest coast have modified marine and coastal ecosystems to enhance food resources, shaping both local biodiversity and ecosystem structure since Time Immemorial. Forest Gardens near villages enhance food plant abundance and diversity, while Clam Gardens and managed clam beds improve clam productivity in the intertidal zone. Today these sites remain vital for cultural practice, food security, and conservation but face various human-caused threats, including climate change, development, and resource extraction. Our research in Gitga’at Territory combines archaeology and ecology to study these cultivated ecosystems, documenting their history and informing future policy along a rapidly changing coast.

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Faculty Supervisor:

Camilla Speller

Student:

Partner:

World Wildlife Fund Canada (Toronto, ON)

Discipline:

Life Sciences

Sector:

Other services (except public administration)

University:

The University of British Columbia

Program:

Accelerate

A Multimodal AI System for Intelligent Hazard and Operability Analysis in Process Industries

This project will explore how artificial intelligence (AI) can make safety reviews in industrial plants faster, smarter, and more reliable. The intern will help build a computer system that can read and understand technical drawings and documents used in engineering, then use that information to spot possible risks in how equipment is designed or operated. By using advanced AI tools like language models and image recognition, the system will help safety teams identify hazards earlier and suggest ways to fix them. This will save time, reduce human error, and improve how safety checks are done. The partner organization will benefit from early access to this new technology, which can make their safety processes more efficient and help prevent accidents in complex systems.

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Faculty Supervisor:

Homayoun Najjaran

Student:

Partner:

HazopCA Inc.

Discipline:

Engineering

Sector:

Professional, scientific and technical services

University:

University of Victoria

Program:

Accelerate

Évaluation de l’utilité des mesures objectives et subjectives de la charge d’entrainement des artistes de cirque

La gestion de la santé physique et mentale des artistes de cirque est un défi, car les exigences varient beaucoup selon les disciplines de cirque. Actuellement, le suivi de la charge de travail, utilisé pour optimiser l’entraînement et prévenir les blessures dans d’autres sports, n’est pas encore appliqué aux arts du cirque. Ce projet vise à développer des métriques adaptées au cirque pour suivre la charge de travail des artistes, en intégrant des mesures objectives et subjectives. En évaluant l’efficacité de ces métriques, le projet apportera des solutions pour mieux gérer l’entraînement et la prévention des blessures, tant pendant les entraînements que les spectacles. Les résultats du projet seront essentiels pour améliorer la pratique et la santé des artistes.

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Faculty Supervisor:

Julien Clément

Student:

Partner:

École nationale de cirque (Centre de recherche, d‘innovation et de transfert en arts du cirque)

Discipline:

Engineering

Sector:

Professional, scientific and technical services

University:

École de technologie supérieure

Program:

Accelerate

Changes in Pediatric RSV Hospitalizations after the COVID-19 Pandemic, 2022-2023, Canada: An Active Surveillance Study

The proposed project will be the largest ever study of RSV associated hospitalizations to Canadian tertiary pediatric hospitals. Cases are identified via our national active surveillance program for vaccine-preventable diseases, the Canadian Immunization Monitoring Program ACTive (IMPACT). IMPACT’s pediatric hospital-based active surveillance network provides a rich source of data with rigorous quality control processes and is an integral part of Canada’s vaccine safety monitoring and disease reporting surveillance systems, covering ~90% of pediatric tertiary care beds in the country. The objective is to conduct the data analysis of RSV seasons from 2022-2023 and add this to the current data from 2017-2022. The previous work determined that the burden of RSV in pediatric populations drastically decreased in 2020 due to public health measures during the COVID-19 pandemic, before seeing an increase in 2021. This project aims to evaluate if the burden in the 2022-2023 data continues to reflect the increase as seen in 2021 or if the burden has returned to rates seen prior to the COVID-19 pandemic. The study will allow public health professionals to make recommendations regarding surveillance of RSV in pediatric population going forward.

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Faculty Supervisor:

Joseph Cox

Student:

Partner:

McGill University Health Centre

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

Research Institute of the McGill University Health Centre

Program:

Accelerate

Assessing the Burden and Outcomes of Acute Respiratory Infection among Children with Medical Complexity at The Hospital for Sick Children

Given advancements in medical and surgical technology, the number of children with medical complexity (CMC) is rising. These children, who experience multiple chronic medical conditions and require ongoing specialized therapies, are at higher risk of adverse outcomes from respiratory infections. However, most research on respiratory infections among CMC has been limited by small sample sizes. This project aims to study disease outcomes and hospital resource needs among CMC hospitalized with respiratory viral infections. This project will use data collected from the READAPT-Kids study at two large children’s hospitals in Canada from 2022-2023, which included nearly 300 CMC hospitalized with respiratory viral infections. In this project, the intern will analyze patient characteristics, presenting symptoms, respiratory virus testing, laboratory and vital indicators, hospital resource utilization, and disease severity outcomes which occurred during hospitalization. The project can benefit SickKids by improving care, management, and hospital resource utilization for CMC by informing clinical decision-making for CMC presenting with acute respiratory infections.

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Faculty Supervisor:

Shelly Bolotin

Student:

Partner:

The Hospital for Sick Children

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Public administration

University:

University of Toronto

Program:

Accelerate

High-throughput selection of monoclonal antibodies against GPCRs using a microfluidic single cell screening platform

Antibodies are biomolecules naturally produced by immune cells, called antibody-secreting cells, to protect against
infection and diseases. Each antibody-secreting cell makes a unique type of antibody that binds specifically to a target molecule. A major challenge in developing antibody therapeutics is selecting the most effective antibodies from the billions produced within any given host.
Our aim is to build on an established technology platform that uses analysis of very small volumes (1/10^9 liters) in
miniaturized devices (microfluidics) to select antibodies against challenging membrane receptor targets directly from
single cells. This project will advance new and innovative solutions to antibody drug discovery such as: finding
antibodies against difficult drug targets; improved capabilities in the selection of antibodies; and high-value
applications in vaccine development and improved approaches to immunotherapy. The work done in this project will
be directly transferable to AbCellera and bring important new capabilities to their technology platform.

View Full Project Description
Faculty Supervisor:

T. Michael UnderHill

Student:

Partner:

AbCellera

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

The University of British Columbia

Program:

Elevate

An Examination of the Biological Impacts of Ocean Alkalinity Enhancement in Halifax Bay via Biogeochemical Observations

The increasing severity of climate change and glacial pace of emissions reform is requiring the development of new strategies for atmospheric CO2 drawdown. One of the approaches that has been gaining traction is Ocean Alkalinity Enhancement (OAE), a method that increases the physical absorption of atmospheric CO2 into the ocean by dispersing alkaline materials in the ocean. The urgency of the climate crisis requires immediate action to understand how OAE can be best implemented to avoid negative biological consequences. To help remediate this uncertainty, this project will merge the expertise of the LaRoche Lab with the instrumentation of the Cassar Lab. In the past two years, large scale alkalinity release has been underway in Halifax Bay (just miles from Dalhousie University). During the visit, Niva will spend one week using a novel instrument to continuously monitor how the ecosystem metabolic rates differ according to proximity to the alkalinity release point in the bay. This will allow quantification of how the ratio of photosynthesis to respiration (an indicator of community fitness) varies according to the intensity of the alkalinity perturbation. The remainder of the visit will be spent in the lab working on short-term cell culture incubations quantifying alkalinity sensitivity.

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Faculty Supervisor:

Julie Laroche

Student:

Partner:

Duke University

Discipline:

Earth science

Sector:

Education

University:

Dalhousie University

Program:

Globalink Research Award

Turbulence-driven flow control for efficient passive and active battery cooling in electric vehicles

This project aims to develop advanced hybrid cooling strategies for electric vehicle (EV) battery systems by integrating turbulence-enhanced flow control with passive air and active liquid cooling methods. Using an unsteady Reynolds-averaged Navier-Stokes k-omega model, the research will investigate the role of turbulence in improving heat dissipation, temperature uniformity, and overall thermal performance. By combining fluid dynamics expertise with cutting-edge thermal management techniques, the project seeks to deliver efficient, lightweight, and cost-effective cooling solutions for next-generation EVs and energy storage systems, contributing to cleaner transportation and sustainable energy innovation.

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Faculty Supervisor:

Baafour Nyantekyi-Kwakye

Student:

Partner:

Kwame Nkrumah University of Science and Technology

Discipline:

Engineering

Sector:

Automotive; Technology; Transportation (excluding aerospace)

University:

Dalhousie University

Program:

Globalink Research Award

Nano-biostimulant derived from fish byproduct to improve plant growth and productivity

Global fish and seafood consumption has increased, leading to large amounts of byproducts from fish markets and processing industries. Currently, the byproducts are used to produce fish meals or dumped into the ocean, causing suffocation and introducing diseases and noxious species. Other potential uses such as bioconversion into biostimulant for agricultural use. Fish are rich sources of proteins, lipids and minerals. Therefore, their byproducts formulated as biostimulants is expected to contain high mineral nutrients, lipids, proteins and amino acids essential for plant growth and health-promoting bioactive compounds in harvested food crops. The proposed research will use fermentation process and nanotechnology to develop a new fish byproduct biofertilizer, which will be tested on kale plants. The intern will study the effect of biostimulant on kale seed germination, seedling establishment and plant growth. It is anticipated that this project will 1) develop efficient and innovative biostimulant to increase plant growth and stress tolerance; 2) improve quality and health-promoting phytonutrients in harvested plants; and 3) help divert large volume of fish byproducts from landfills and water bodies for recycling into a high value bioproduct with a long-term social, health, economic and environmental benefits.

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Faculty Supervisor:

Lord Abbey

Student:

Partner:

Meru University of Science and Technology

Discipline:

Life Sciences

Sector:

Agriculture and Food; Nanotechnology; Life Sciences (not health)

University:

Dalhousie University

Program:

Globalink Research Award

Generation of rabbit monoclonal antibodies using a microfluidic-based screening platform – Year two

Rabbits are increasingly recognized for their superior immune response to antigens and their ability to generate highaffinity monoclonal antibodies (mAbs) that can be used as reagents, diagnostics and therapeutics. However, methods for the discovery of rabbit mAbs are limited and extremely cumbersome. This proposal aims at developing a rapid and robust microfluidic-based approach to generate rabbit mAbs by directly screening immune cells for defined antibody properties.

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Faculty Supervisor:

T. Michael UnderHill

Student:

Partner:

AbCellera

Discipline:

Life Sciences

Sector:

Professional, scientific and technical services

University:

The University of British Columbia

Program:

Elevate

Early Detection of Grain Spoilage and Contamination Using Hybrid NIR-E-Nose Systems with Machine Learning

This project explores the feasibility of using a hybrid sensing system that combines Near-Infrared Spectroscopy (NIR) and Electronic Nose (E-Nose) technologies, enhanced by machine learning, to detect early signs of spoilage and contamination in stored grains. By analyzing changes in grain structure and gas emissions, the study contributes to ongoing research on reliable, non-destructive, and timely solutions for monitoring grain quality during storage. Such systems can help reduce post-harvest losses, support food safety and sustainability, and improve decision-making in grain handling and storage operations.

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Faculty Supervisor:

Mohammad Nadimi

Student:

Partner:

University of Barcelona

Discipline:

Engineering

Sector:

Education

University:

University of Manitoba

Program:

Globalink Research Award