CAN-BIND12: Effects of Probiotics on Symptoms of Depression (EPSD)

This study will look at changes in the heart rate variability and electroencephalogram (EEG) signals in individuals receiving gut supplementation for depression. This is to see if the vagus nerve (a major nerve connecting your brain and gut) is affected by this therapeutic, and how that results in changes in your brain. This work will provide insight into the mechanism of action for these supplements and contribute to a great understanding of major depressive disorder and possible avenues for advancement in the realm of gut microbiome targeting MDD treatments. This will be beneficial for the partner organization as they will gain a better understanding of how their therapeutic works, and possible ideas for how they can improve its efficacy in the future.

Faculty Supervisor:

Roumen Milev


Evan Forth;Caroline Wallace


Lallemand Health Solutions





Queen's University



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