Dentin Collagen Methacrylation for Tooth-Restoration Bonding

The most employed treatment for decayed teeth is restoration with resin-based filling materials. Longevity of resin fillings is considered low, around 7-10 years. Replacement of resin fillings accounts for 75% of all procedures performed in general practice, of which 60% are due to failures at tooth-filling interface. This happens because during bonding procedure the tooth mineral is dissolved by acids exposing the tooth organic component and enzymes that can degrade tooth structure. Moreover, the micromechanical attachment between filling material and tooth, and the lack of a strong chemical interaction between the two structures, produces a porous interface which is prone to saliva and bacteria infiltration leading to failures over time. We have developed a filling material that inhibited the activity of dentin enzymes. Here we propose to chemically modify tooth structure, which will allow for a strong chemical bond between tooth and the anti-enzymatic resin. This should considerably improve the success rates of dental fillings. This will be developed with the University of Sao Paulo. With this exchange, students will gain exposure to different cultures, which will enhance their global awareness and intercultural communication skills. Both universities will strengthen academic ties, and foster innovation through diverse academic environments and resources.

Faculty Supervisor:

Anuradha Prakki

Student:

Partner:

Universidade de São Paulo

Discipline:

Engineering

Sector:

Education

University:

University of Toronto

Program: