Designing quality control strategies to assess the self-assembly and biological stability of chitosan nanoparticles

In this grant, the consortium will develop new methods to characterize nanoparticles prepared with a proprietary polymer. This study will enable the fabrication and characterization of better performing nano-sized particles encapsulating therapeutic molecules, commonly called nanomedicines. This study will allow to monitor how the polymers self-assemble into nanoobjects under different conditions, and to study how the nanoparticles perform in various environments. The project will develop and validate methods to streamline the development of nanoparticles with a variety of characteristics. Eventually, this technology will translate into the development of a new generation of drugs to treat various important human ailments, notably cancer, antibiotic-resistance, and neurologic diseases.

Faculty Supervisor:

Nicolas Bertrand

Student:

Amrita Dikpati

Partner:

Ovensa Inc

Discipline:

Pharmacy / Pharmacology

Sector:

Nanotechnologies

University:

Program:

Accelerate

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