Discovery of Endocannabinoid modulating compounds for Alzheimers disease therapeutics development

Alzheimers is the most common form of dementia which worsens over time. Current therapeutic against Alzheimers disease provides only symptomatic treatment. This limited effectiveness provides us with an opportunity to direct our research efforts towards developing new agents to prevent or retard the disease. Studies have shown that very small amount of tetrahydrocannabinol (THC), a chemical found in marijuana, can slow the production of Amyloid beta (A?) protein. This protein is found to be the hallmarks of Alzheimers disease and a key contributor in its progression. Our study aims at removing the psychoactive component from marijuana, retaining it therapeutic part and screening those compounds to find a potent drug against Alzheimers disease.

Faculty Supervisor:

Kagan Kerman

Student:

Aruna Raja

Partner:

Lupos

Discipline:

Chemistry

Sector:

Life sciences

University:

Program: