Dual Cobalt/Photoredox Catalyzed Synthesis of Urea-Type Containing Heterocycles

A key goal in modern organic chemistry is the development of efficient synthetic routes to access industrially relevant structures starting from highly abundant feedstock chemicals, while minimizing the use of expensive rare-earth metals for catalysis. This project aims to synthesize urea-type containing heterocycles, which are a common structural feature found in many biologically active compounds, through the combination of cobalt and organophotoredox dual catalysis. The starting materials for this transformation are easily accessible, allowing for a variety of previously difficult to access compounds to be achieved in a simple one step procedure. Success of this project could result in this methodology being applied on a larger scale in an industrial setting. By collaborating between the University of Toronto and Kyoto University, the transfer of knowledge between two internationally renowned institutions could result in further advances in the scientific community through the mutual sharing of expertise.

Faculty Supervisor:

Mark Lautens

Student:

Partner:

Kyoto University

Discipline:

Physics

Sector:

Education

University:

University of Toronto

Program: