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Osteoarthritis is a major cause of disability in dogs. Today, the therapeutic role of mesenchymal stromal cells (MSCs) as a potential treatment for immune and inflammatory disorders is well-defined. We are interested in exploring the immune-modulatory property of canine MSCs with the aim of exploiting it as a potential therapy in dogs with Elbow Dysplasia. This foundational work will support future funding applications to conduct a randomized clinical trial (RCT) to evaluate the effectiveness of the treatment. This project will provide a baseline for a long-term research program to discover new drugs and/or cell-based products that can develop novel treatment strategies to help osteoarthritis patients.
Jonathan LaMarre
Sahar Mehrpouyan
eQcell
Biochemistry / Molecular biology
Professional, scientific and technical services
University of Guelph
Accelerate
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