Enzymatic nano-immobilisation facilitated by 2D materials for antifouling coatings – Year two

Enzyme immobilisation is crucial for preserving the enzyme activity while enabling the enzymes to be recovered and reused for multiple applications in biocatalysis. However, immobilisation can change the structure and functionality of enzymes. Therefore, immobilisation of enzymes needs to be carefully investigated and controlled at fundamental levels. The emerging two-dimensional (2D) materials, such as graphene and transition metal dichalcogenides exhibit unique physico-chemical properties which make them well suited for enzyme immobilisation. Considering this, our research will focus on the use of 2D nanomaterials as enzyme immobilisation materials to modify and control the stability, selectivity and activity of various enzymes. Through this project, we will design novel green routes for the production of biocompatible 2D materials to be used as immobilisation supports for various types of enzymes. This will assist in understanding the enzyme nano-immobilisation mechanism and will open new applications for the functionalized 2D materials in enzymatic nanobiotechnology. Specific enzyme-immobilised 2D materials developed with the partner company of Biosa Technologies, will possess bactericidal properties which will be applied for producing antifouling coatings for food preservation. This project will provide Biosa significant scientific and technological achievement and commercial success in improving enzymatic technology and enhancing antimicrobial coatings market in Canada.

Faculty Supervisor:

Hadis Zarrin


Jasneet Kaur


Biosa Technologies


Engineering - chemical / biological


Professional, scientific and technical services


Ryerson University



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