The goal of the project is to determine if the cannabis-derived, non-psychoactive compound, cannabigerol (CBG) (a key component of Cannabis), which is known to reduce inflammation in a mouse model of colon inflammation, can also prevent intestinal strictures (fibrosis) and narrowing of the intestine in the setting of intestinal inflammation. We will use cell culture and animal models that develop key features of fibrosis, to determine if CBG can prevent fibrosis and stricture formation. The data will be directly relevant to preventing fibrosis in patients with inflammatory bowel disease, which has a high incidence in Alberta and Canada.
Morley D Hollenberg
Vivek Krishna Pulakazhi Venu
Pharmacy / Pharmacology
Find the perfect opportunity to put your academic skills and knowledge into practice!Find Projects
The strong support from governments across Canada, international partners, universities, colleges, companies, and community organizations has enabled Mitacs to focus on the core idea that talent and partnerships power innovation — and innovation creates a better future.