Higher versus lower load resistance training in young men

There is substantial variability in an individual’s ability to increase muscle mass following resistance exercise training (RET). The final chapter of my doctoral thesis is designed to explore the relative influence extrinsic (e.g., the load lifted per repetition) vs. intrinsic (e.g., rates of protein turnover) factors have on RET-induced muscle hypertrophy. I am applying for the Globalink Research Award to learn dynamic proteome profiling from the method’s pioneer (Dr. J. Burniston). We propose that dynamic proteome profiling will elucidate rapid protein turnover of hundreds of proteins following the initial bouts of RET, and that the specific protein turnovers will be altered by chronic RET. In addition, we expect myofibrillar proteins to be markedly different between individuals and that their rates of turnover will be aligned of muscle hypertrophy following chronic RET. TO BE CONT’D

Faculty Supervisor:

Stuart Phillips

Student:

Partner:

Liverpool John Moores University

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology

University:

McMaster University

Program: