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The discovery and development of antimicrobials as therapeutic agents has transformed modern medicine. However, their further mass production, global distribution, and gross misapplication have resulted in escalating emergence of multi-drug resistant (MDR) bacteria worldwide. Given the limited arsenal of antimicrobials available to combat MDR bacteria, there is growing apprehension about the threat posed by “superbugs” and a pressing need for novel therapeutics. Natural clay minerals have a long history of therapeutic and biomedical applications and lately received increasing attention for their antimicrobial properties. Kisameet clay (KC), a naturally-occurring clay mineral, has been long known for its therapeutic properties. Recently, we demonstrated the potent and broad-spectrum antimicrobial activities of KC against a variety of MDR bacterial and fungal pathogens have been described. The research described here may provide a better understanding of the principal components of KC antibacterial activity and create a basis to develop defined preparations of KC for therapeutic applications.
Julian Davies;Michael Murphy
Kisameet Glacial Clay Inc.
University of British Columbia
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