Nanoscale toolset for formatting and visualizing single molecules: validating applications and miniaturized flow cells

The “CLiC” microscopy technique was invented and developed by Prof. Sabrina Leslie and her lab at McGill. It is ideal for formatting and visualizing single molecules, like DNA and proteins, with advantages that overcome the limitations of other single-molecule techniques. Due to the increasing interest in the technique from academic and industrial researchers, Prof. Leslie has launched a start-up company called ScopeSys to commercialize this valuable research tool. The launch product consists of a small add-on device to a microscope and consumable flow cells, which the company is currently making available to a handful of early-access researchers in the biophysics, nanotechnology, and biomedical research fields. An obstacle to CLiC’s commercialization is that the flow cells are fabricated using standard-size (25-mm) glass cover slips and assembled by hand; a process which is time-consuming and expensive. TO BE CONT’D

Faculty Supervisor:

Bradley Siwick


Albert Kamanzi


ScopeSys Inc.


Physics / Astronomy


Information and communications technologies




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