Optimization of conformational epitopes against the NTS1 and P2Y6 receptors

The proposed project, performed with the company Immune Biosolutions, aims to develop superior antibodies for biological targets of interest for the treatment of colorectal cancer. Specifically, these targets are a class of proteins expressed on cell surface, which are notoriously difficult for the development of antibodies. The method involves making molecules look like the biological target, in order to elicit antibody responses which are more specific to the targets. The proposed project will have a technological impact that will make biomedical research more reliable by providing better tools, as well as a translational impact by providing molecules to validate new targets for the treatment of colorectal cancer.

Faculty Supervisor:

Philippe Sarret


Marie-Edith Nepveu-Traversy


Immune Biosolutions


Pharmacy / Pharmacology


Medical devices




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