The aim of this grant proposal is to address the challenges with current CT Coronary Angiography (CTCA) utilization with a comprehensive series of interrelated but well-defined research themes. This non-invasive technique has facilitated in the detection of significant coronary artery disease and vulnerable plaque. However, the quality is limited to the physicality of the patients in particular to the population who are at the greatest risk of coronary arterial diseases (CAD). Each student will undertake research projects that will resolve several important limitations in the use of current CT technology for accurate evaluation of coronary patency and plaque characterization. These include 1) in-plane Temporal Resolution, 2) Spatial Resolution, 3) Contrast Resolution, 4) Radiation Dose, and 5) Post-Processing Vessel and Plaque Analysis Tools.
Drs. Narinder Paul, Richard Cobbold & Willy Wong
Toshiba Medical Systems
University of Toronto
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