Secondary cataract assessment in eyes implanted with different intraocular lenses

Cataract surgery is one of the most common surgeries performed worldwide. The incidence of posterior capsule opacification (PCO) after cataract surgery, a serious complication that affects vision and requires additional treatment, is ~30%. In this study, we will investigate differences in PCO, presence of fibronectin, and ciliary ring distortion between lenses in eyes obtained from private and public eye banks. Overall, 500 eyes from patients with intraocular lenses will be analyzed. PCO, presence of fibronectin, and ciliary ring deformation will be assessed by experienced pathologists. We believe that our results will corroborate a pilot project in which eyes implanted with Acrysof and Acrysof Natural lenses (Alcon Laboratories) will experience less PCO relative to other lens types. Alcon will be able to market their products using these data. Moreover, healthcare providers will be encouraged to increase their use of the Acrysof products, thereby reducing the the overall burden of PCO.

Faculty Supervisor:

Miguel Burnier

Student:

Patrick Logan

Partner:

Alcon Canada

Discipline:

Medicine

Sector:

Life sciences

University:

McGill University