THE ANTI-INFLAMMATORY POTENTIAL OF NATURES IMMUNO ON INFLAMMATION INDUCED BY LPS

Inflammatory diseases such as pulmonary inflammation, lung cancer, asthma, and fibrosis exert a great economic impact across the globe. They have a tremendous impact on health and quality of life. Proinflammatory cytokines are released by the immune system which can be activated by Lipopolysaccharides (LPS), an endotoxin which mimics infection by Gram-negative bacteria. The literature indicates that females are at an increased risk of developing inflammatory diseases compared to males. NATURES IMMUNO is an innovative formula developed by NHV Natural Pet Products to support the immune system. It is extracted from 5 commonly used mushrooms: Turkey Tail mushroom, Coredyceps mushroom, Reishi mushroom, Shiitake mushroom, Agaricus mushroom. However, the influence of the combination of these mushrooms on the immune system is not well understood. Based on the theoretical benefits of the mushurooms contained in NATURES IMMUNO formulation, we will conduct a series of studies to explore the efficacy, safety, and anti-inflammatory properties of NATURES IMMUNO. Through this research, we aim to observe the effect of NATURES IMMUNO on inflammation caused by LPS in male and female mice. NHV will be benefit from the experimental data that can prove the efficiency of NATURE IMMUNO formulation through marketing.

Faculty Supervisor:

Shelley Kirychuk

Student:

Amanda Florentina do Nascimento

Partner:

NHV Natural Pet Products

Discipline:

Agriculture

Sector:

Life sciences

University:

University of Saskatchewan