Related projects
Discover more projects across a range of sectors and discipline — from AI to cleantech to social innovation.
Dysfunction of vital organs is one major reason why trauma victims die after sustaining a major injury, even though the organs themselves may not have been directly injured. One intervention proposed to prevent development of distant organ injury is called “Remote Ischemic Preconditioning” (RIPC), wherein application of intermittent occlusion and release of blood flow to a limb by sequentially inflating and deflating a blood pressure cuff. This project will study mechanisms whereby RIPC protects the liver after hemorrhagic shock, which may help suggest alternative or additive beneficial interventions to those achieved with RIPC. In addition, in a pilot study, we will investigate the effects of RIPC in trauma patients, with specific focus on the coagulation and immune systems, both known to be deranged in these patients. These studies will potentially benefit patients and serve as proof of principle for the use of the CellAegis RIPC device in the trauma setting.
Dr. Ori Rotstein
Chung Ho Leung
CellAegis Devices Inc.
Medicine
Medical devices
University of Toronto
Accelerate
Discover more projects across a range of sectors and discipline — from AI to cleantech to social innovation.
Find the perfect opportunity to put your academic skills and knowledge into practice!
Find ProjectsThe strong support from governments across Canada, international partners, universities, colleges, companies, and community organizations has enabled Mitacs to focus on the core idea that talent and partnerships power innovation — and innovation creates a better future.