The use of a fast platform to design and develop anti-SARS-CoV-2 peptides for a therapeutic intervention of COVID-19

We are attempting to cure COVID-19! This is a very important initiative! Currently, no cure or vaccines are available to combat SARS-CoV-2. There is an immediate need to develop such therapies. The importance of developing a cure for COVID-19 cannot be overstated! Here, we propose an alternative approach to traditional drug development methods. Our approach provides a very fast and cost-effective method to develop anti-COVID-19 therapies. It is well established that the viral S protein that binds to the human ACE2 receptor. This interaction mediates the entry of the virus into the human cell where the virus replicates. Here, we propose to use an alternative computational tool to design peptides to bind to S protein and inhibit its binding to the human ACE2 protein or alternative proteins needed for virus replication in the cell.

Faculty Supervisor:

Ashkan Golshani

Student:

Maryam Hajikarimlou

Partner:

Orpheus Medica Inc.

Discipline:

Biology

Sector:

Professional, scientific and technical services

University:

Carleton University