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Title of project:In vivo and in silico evaluation of multiorgan variability for the detection of criticalphysiological changes of patients in Intensive Care Units
The project focuses on the characterization of the evolution with time of the properties of
physiological signals recorded in different clinical settings, describing sepsis shock and other
clinical complications that are common features in Intensive Care Units. Changes in heart
rate, respiratory rate, blood pressure and oxygen saturation will be studied through an array
of more than 70 techniques; some will consider the signals one-at-a-time, others will analyze
the signals simultaneously. The final objective is characterizing the interrelationship between
the different techniques and their clinical relevance in the detection of changes in the
physiological conditions of patients in the ICU. The long term goal is using the collect results
to create predictors of those changes, promoting a shift from o descriptive medicine, where
predictive medicine, where the disease is detected before having deleterious effects on the
patients, improving diagnosis and treatment of illnesses.
Faculty Supervisor:
André Longtin
Student:
Partner:
Therapeutic Monitoring Systems Inc (Ottawa, ON)
Discipline:
Physics
Sector:
Professional, scientific and technical services
University:
University of Ottawa
Program:
Accelerate
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