Decision-making frameworks for Health Technology Assessment (HTA) have become a major topic in developed nations in recent years. Indeed, the quest for more rational and transparent HTA decisions led many jurisdictions to investigate the use of Multi-Criteria Decision Analysis (MCDA) as an alternative decision-making framework. In Canada, the development of a MCDA framework for HTA […]

1 in 5 people suffer from a mental illness, such as depression, Alzheimer’s & Parkinon’s during their lifetime. Currently, there are no treatments for these diseases, because the underlying causes of these diseases is not known. Neurescence has developed a technology that is essential for understanding how local and long-range neuronal circuits form to create […]

Coffee is one of the world’s most popular beverages due to the delivery of caffeine and diverse flavours. The genetics of how caffeine is processed in the human body is fairly well understood. With the decrease in cost and increase in popularity of consumer genetics, we are interested in learning how modern genetic analysis techniques […]

Social medias data bases are important for continuous and automated Adverse Drug Reactions (ADRs) surveillance. Predicting ADRs can reduce the related mortality. A systematic review of the medical scientific literature is required for tracking and identifying the risk/benefit ratio of drugs and safety issues. The implementation of means of standardizing patient’s language used in social […]

Blood sugar levels increase after the consumption of food. Especially in sugary foods such as candy or chocolate, this increase in blood sugar will be more pronounced. In individuals with diabetes, who may require tracking of carbohydrates and food or injection of insulin following a meal, foods such as chocolate are suggested to be avoided. […]

There is a growing body of evidence that certain combinations of bioactives derived from natural source products may have potent effect on neuritogenesis and foster neuronal cell viability. The effect of neuron plasticity suggests there are potential treatments of major neurodegenerative and psychiatric conditions. In this project we are proposing to use a robust in […]

Air pollution is linked to 7 million deaths worldwide, making air quality one of the top ten global causes of death. Eighty percent of Canadians live in cities, and growing evidence suggests that indoor air within the built environment has significant health impacts. Our research will evaluate the contaminant removal capabilities of an active ‘living […]

In order to investigate proteins in their natural environment one can attach tiny reporter molecules to them that can be traced with appropriate instruments. However, these small reporter molecules may often cause strong perturbations to the functionality of the proteins, or cannot be seen due to experimental restrictions like low concentrations. Bioorthogonal chemistry aims to […]

The world is currently facing a biodiversity crisis driven by the loss and degradation of habitat resulting from the conversion of natural areas to agricultural land and urban development. To combat this biodiversity crisis, the government committed to Convention of Biological Diversity and national targets of protecting at least 17% of terrestrial land through network […]

Children that break their bones repeatedly often have genetic conditions that either affect bones directly or indirectly. The drugs that are currently used to decrease the number of fractures in children are only partially effective. Mesentech Inc. has developed a new drug that has shown a strong effect on bone formation in rats. In this […]

Global biodiversity is declining due to habitat loss and protected areas provide an opportunity to prevent this. While governments create and manage most protected areas in the world, non-governmental organizations can also play a significant role in the acquisition and management of properties for the purpose of conserving biodiversity. We propose to measure the Nature […]

Activation of the immune system is necessary for defense against pathogens and injury, but just as important are the processes to turn this inflammatory response once the infection or injury has been resolved. Inappropriate prolongation of immune cell activation results in inflammatory diseases such as inflammatory bowel disease, asthma and arthritis. The University of British […]