Investigations into the mechanism of action and potential in idiopathic pulmonary fibrosis of the novel ruthenium based therapeutic BOLD-100

Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease lung disease with unknown cause. There are limited treatment options for IPF and investigations into new treatment options is needed. BOLD-100 is a clinical-stage small molecule that is currently being investigated as a treatment option in oncology and viral infections. The pathway that BOLD-100 impacts, […]

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Oilseed with Depleted Glycosides

Flax seed is of interest as a health food product with high omega-3 fatty acid, protein and fiber content. The seeds naturally contain compound that are anti-nutritive and have a bitter flavor. We have developed a process to safely and cheaply remove these compounds from whole flax seed. We intend to investigate the nutritive qualities, […]

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Développement d’une stratégie pancanadienne pour la gestion de la résilience des infrastructures naturelles

Face aux changements globaux, nos infrastructures naturelles, et donc les services qu’elles produisent, sont fortement menacées et le risque de les voir disparaître est de plus en plus inquiétant Ainsi, afin de maintenir – voire augmenter – les services rendus par nos infrastructures naturelles pour le bénéfices des 83% de canadiens vivant en milieux urbains, […]

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Impact of Bioavailable Peptides Generated from Collagen Hydrolysates on Bone Remodeling

Genacol Canada Corporation Inc. manufactures a collagen hydrolysate (CH) product, sourced from bovine (Genacol® Original Formula), that has shown promising and positive results in three clinical trials for decreasing joint pain, as well as having a positive effect on articular cartilage. Following digestion, and first pass metabolism, CHs release peptides that have been shown to […]

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How can hormone monitoring can improve women’s health?

Eli Health is developing a novel biosensing device to monitor sex hormones in saliva and a mobile application that leverages machine learning to interpret them. The mission of the organization is to enable women to take control of their health across their lives. It will first commercialize the device for fertility and contraception applications. In […]

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Validation of the Rootd App for Reducing Anxiety and Panic Attacks

During the COVID-19 pandemic, it’s become quite apparent that mental health needs to be prioritized. Due to the demands of social isolation, getting adequate mental health support can be difficult. However, the mobile application Rootd provides a low-cost and large-scale solution to this problem, as it can help the average person deal with increased anxiety […]

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Accelerated development of a recombinant protein vaccine against COVID-19 by integrating the SARS-CoV-2 S-protein antigen with a new delivery system

The objective of this proposal is to develop a new candidate recombinant protein vaccine for the new coronavirus disease 2019 (COVID-19) based on a novel protein delivery and adjuvant technology, iPDT. If successful, this research will advance another COVID-19 vaccine candidate(s) to the pipeline toward clinical use. The causative agent of COVID-19 is SARS coronavirus […]

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Evaluation of terminal complement cascade inhibitors using in vitro and in vivo models of age-related macular degeneration and in Alzheimer’s Disease

Age-related macular degeneration (AMD) is a leading cause of blindness that is estimated to affect over 6 million people globally. There are currently no approved treatments for dry AMD, the most common form of the disease. Various lines of inquiry suggest that dysregulation of a part of the innate immune system called complement plays a […]

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