Digitized neuroanatomical map of the human saphenous nerve

Overactive bladder (OAB) is an incurable, chronic medical condition that is characterized by symptoms of urgency, frequency, nocturia and urinary incontinence. It affects approximately 18% of adults and over 30% of the elderly population. Saphenous nerve stimulation is a novel therapy aimed at treating OAB patients. It offers an alternative to bladder medication, which can […]

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Plant-sourced high-performance fibres for the production of novel textiles

The multi-billion dollar fashion industry has a problem: many of the high-performance fabrics used in clothing are neither sustainably produced or environmentally friendly. However, there is a considerable market gap in sustainable textiles. Canadian corporations like Proteins Easy Corp are tackling the sustainability problem head on and actively seeking environmentally friendly solutions. This proactive approach […]

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Enrichment strategy for cardiovascular clinical trials

Cardiovascular clinical trials try to demonstrate the benefit of a medication on populations where the number of participants with the targeted disease is very low. The low efficacy of treatment is partially due to the diversity of diseases and of the population. To improve the efficacy of treatment, it is necessary to improve the recruitment […]

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Elaboration of a high-throughput toolbox for analysis and visualization of mesoscale longitudinal cortical imaging dataset

The analysis of large, complex data helps scientists from different fields (e.g. physics, chemistry, biology) to provide new insights on their research. The field of neuroscience is no different. Larger and more complex studies which create huge amount of data are more and more common. Thus, the development of tools capable of processing large datasets […]

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Investigation of immunological mechanisms ofpeptide immunotherapy

A[though early clinical trials have been positive, peptide vaccine mechanism of action (how tolerance is induced) is unknown. The primary objective of these studies is to identify changes in gene expression and cytokine expression that are correlated with vaccine treatment. These changes could provide insight to mechanisms of action and may reveal potential genetic biomarkers […]

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EVestG Optimization as a diagnostic tool for Meniere’s disease

Dizziness is among the top three reasons that patients seek medical attention, and one of the most common disabling conditions that humans face. One of the diseases that may cause dizziness is Meniere’s disease, which its correct and timely diagnosis and separation from other causes of dizziness with current techniques are quite challenging. On the […]

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Scaling up algaculture by the use of a novelcirculation technology while optimizingproductivity by testing for the effects of lightintensity and C02 supply rate.

This project will address the scalability problem that currently exists in algaculture. Scaling up algae production to the industrial level has been challenging. The reason’ being that productivity of photosynthetic algae is highly dependent on light and CO2 availability, which become less available as photobioreactor (algae tank) size increases. The solution is to use circulation […]

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Assessment of two novel chemical entities in theamelioration of tau-related neuropathology andbehavioral impairment in the P301S mouse.

The onset of symptoms in Alzheimer’s Disease, Picks disease, progressive supranuclear palsy and cortical basal degeneration are connected to the formation of insoluble deposits of the tau protein in the brain, also known as neurofibrillary tangles (NFT). The Treventis Corporation has developed new chemicals that are designed to prevent the formation of NFT, which may […]

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Assessing the immune response to stem cell-derived beta cells and associated bioprinted devices for diabetes cell therapy

Type 1 diabetes (T1D) is an autoimmune disease where pancreatic beta cells are destroyed and no longer produce insulin, a hormone that maintains healthy blood sugar levels. People with T1D must replace insulin with injections or a pump. Although insulin is lifesaving, maintaining normal blood sugar levels is often a struggle for people with diabetes. […]

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