Test de généralisation d’une méthode de quantification de fertilité du sol

Ce projet de thèse vise à étudier les relations entre les traits fonctionnels des plantes et un gradient de fertilité du sol. Pour ce faire, il est nécessaire de développer une méthode et un modèle pour quantifier la fertilité générale d’un sol, qui soit applicable à l’échelle d’une communauté à un ensemble d’espèces. En effet, […]

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Collision avoidance between two walkers: an understanding of children’s behaviours

Collision avoidance can be described as a whole-body movement control problem in which visual information is used to elicit accurate movement adaptations. Previous research has demonstrated that children lack knowledge about their own action capabilities as well as the ability to use vision to properly guide actions in static environment. Little is known about how […]

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Regulation of muscle stem cells during embryogenesis

Duchenne muscular dystrophy (DMD) is a severely debilitating and lethal disease affecting approximately 1in 3,500 male births. In a seminal discovery, the Rudnicki lab discovered that deficits in muscle stem cell asymmetric divisions is a part of the underlying mechanism that results in the progressive wasting of skeletal muscles found in DMD. Dystrophin protein, the […]

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Regulatory networks controlling pathogenesis of the fungal pathogen Candida albicans

Candida albicans is an opportunistic fungal pathogen which is the leading cause of invasive candidiasis, an increasingly drug resistant disease that attacks vulnerable populations. Candida albicans is interesting because it is a commensal organism present in human tissues that can become deadly in response to specific environmental cues. Understanding what governs the shift from harmless […]

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Regional heterogeneity in lake morphology in Ontario

Lake size and shape are important factors determining the function and structure of lake ecosystems. Moreover, Lake morphology is important for both biotic and abiotic processes, including species richness of zooplankton, macrophytes, and fishes. In particular, Ontario has tens of thousands of natural ecosystems that make up a large part of Canada’s dominant share ofthe […]

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Tomographe à positrons à ultra-haute résolution pour l’imagerie d’animaux intermédiaires et du cerveau humain

Le projet global vise le développement d’un scanner de tomographie d’émission par positrons (TEP) dédié à l’imagerie des animaux de taille intermédiaire (chien, macaque) et du cerveau humain. L’avantage principal du scanner sera sa résolution spatiale deux fois meilleure que tout ce qui existe à l’heure actuelle, permettant notamment l’imagerie des processus biochimiques à l’intérieur […]

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Therapeutic Drug Monitoring of Sunitinib and Pazopanib in Advanced or Metastatic Renal Cell Carcinoma (SUP-R)

Sunitinib and pazopanib are two effective medications from tyrosine kinase inhibitor pharmacologic class for the first-line treatment of metastatic renal cell carcinoma (mRCC). Nevertheless, the adverse side effects during treatment often lead to dose reductions or even treatment discontinuations. In order to provide the most efficient treatment to mRCC patients, efficacy and safety of these […]

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Joint Range of Motion, Muscle Strength, and Gait-Derived Ground Reaction Forces Pre and Post Novel Rehabilitation Program for Lower Limb Amputees

This project is being undertaken as a part of the Gait Rehabilitation Analysis for Amputee Locomotion (GRAAL). GRAAL is a 3-year project focused on the continued rehabilitation of people with lower limb amputations. Through this research I will use gait analysis technology to kinetic measures of gait including ground reaction forces and muscle torque and […]

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Experience and Health Impact of University Students Accessing a Digital Nutrition, Fitness and Mindfulness Platform

Universities across Canada are facing a mental health crisis with an increasing number of students reporting anxiety, depression and suicidal thoughts. This is of special concern in first-year undergraduate students. First year university students will be asked to use an electronic platform which encompasses three pillars of health (nutrition, fitness and awareness) for 12 weeks. […]

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Finding innovations to improve calf gastrointestinal health

The neonatal and pre-weaned periods are the most challenging in dairy production, resulting in the highest mortality and morbidity rates, with diarrhea proving the most common cause of calf health problems. In order to treat and control this diarrhea, producers often rely on antibiotic therapy. An alternative is to provide living microorganisms (probiotics) that minimize […]

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