Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

Our aim is to use machine-learning to improve treatment of post-surgical pain in children and adults. Most people addicted to opioids were initially exposed through the treatment of pain from trauma and/or surgery. The opioid crisis is reaching the pediatric population, in whom effective post-surgical pain management, with less reliance on prescription of opioids, is […]

COVID-19 is a global pandemic with no effective therapeutic and preventive agents. Given the high infectivity of the SARS-CoV-2 and severity of the disease, vaccines are urgently needed to tackle the infection of this novel coronavirus. Thus far, various types of vaccine candidates, in different stages of preclinical testing and clinical trials, are being explored, […]

The effectiveness of cancer drugs depends on several factors which are governed by the genetic and ‘epigenetic’ code of cancer cells. The epigenetic code comprises those heritable modifications that bookmark DNA and DNA-associated proteins to guide the expression of genetic attributes without changing the DNA sequence. This epigenetic code is written, read, and erased by […]

The SARS-CoV-2 outbreak, which started in Dec. 2019, has so far not been contained due to unpreparedness and unsuccessful development of antiviral drugs against SARS-CoV-2. In response to this pandemic, we propose development of a diagnostic assay based on saliva samples. We will also standardize virus collection procedure and inactivation steps to reduce the turnaround […]

The project addresses urgent and clinically-relevant questions related to COVID-19, which causes in some patients life-threatening respiratory distress, septic shock and organ failures. Patients in intensive care units were found to have significantly higher levels of high mobility group box 1 (HMGB1) than patients with milder symptoms. HMGB1 is a protein normally found in the […]

COVID-19 pandemic has brought the world to standstill with more than 55 million people infected to-date and more than 1.34 million mortality so far. It has literally brought the health care systems in many countries to the breaking point, if not beyond. The economic consequences have been devastating with millions of people out of work. […]

This research aims to develop and test a transdermal delivery system for small bone healing peptide hormones. Peptides and many drug molecules do not usually penetrate the outer skin barrier, the stratum corneum, in order to treat the underlying body tissues. However, by using liposomal gel as a drug delivery medium, it is often possible […]

The current pandemic has highlighted the need for utilizing virtual care in pharmacy practice to ensure accessibility to medication and pharmacist services while maintaining social distancing to limit the potential of contagion. As pharmacist virtual care becomes more prevalent, it is important to explore the various models that currently exist or are being developed. This […]

To design effective and patient-specific cancer therapy, sensitive detection of relapse and distant metastases by non-invasive medical imaging is essential, for which MRI offers tremendous potential due to wide availability of the equipment in clinic and avoidance of ionizing radiation. Although gadolinium-based contrast agents are the most frequently used for MRI, they are associated with […]

The intern will construct a 3D atlas of the mouse brain, constructed using multiple biomedical and chemical imaging techniques. The atlas will aid visualization of the 3D distribution of brain metabolites and biomolecules.. The atlas will be a powerful research and teaching resource with its multi disciplinary approach to processing and visualizing data collected at […]

The COVID-19 pandemic reminds us that, first, global pandemics are significant threats to population health and material standard of living and, second, evidently not enough is being done to prevent pandemics. Future pandemics are likely if the system of pandemic preparedness is not improved. The first step to ensure we are ready for the next […]