COVID-19 is a global pandemic with no effective therapeutic and preventive agents. Given the high infectivity of the SARS-CoV-2 and severity of the disease, vaccines are urgently needed to tackle the infection of this novel coronavirus. Thus far, various types of vaccine candidates, in different stages of preclinical testing and clinical trials, are being explored, […]

Teaching through the arts has often been heralded as an effective way to engage marginalized students. As such, it would seem that an arts-infused approach to learning may promote equity and inclusion in schOOls. This research project endeavours to engage students as co-researchers to investigate how exactly the arts and creativity allow moments of equity […]

The politics of information, and information availability, affect civil society’s ability to participate in democratic governance and the ability to establish accountability and credibility. New nonprofit regulations create additional reporting requirements, but much of this information is withheld from the sector itself. The proposed project will produce reports on the data environment of each region […]

The purpose of this project is to identify bees and evaluate plant-pollinator networks based on the biomonitoring surveys conducted at the Meadoway in 2020 in partnership with the Toronto and Region Conservation Authority (TRCA). The aim of these surveys is to develop a baseline understanding of bee diversity in the Meadoway and evaluate the impacts […]

The Guided Therapeutics (GTx) Core of the Techna Institute is developing innovative imaging technology and therapeutic approaches, and translating those advances to commercial and clinical applications. Working with our industrial partners Precision X-Ray and Elekta, the Mitacs-supported interns will develop new capabilities and tools for preclinical image-guided radiation therapy devices and radiosurgical techniques. With Precision […]

Type 2 diabetes is characterized by insulin resistance and has been associated with increased lipids (fat) in the blood (hyperlipidemia). Our research focuses on regulation of blood lipid levels by controlling both intestinal and liver fat (lipid/lipoprotein) metabolism. We have previously shown in our laboratory that a naturally occurring hormone called glucagon-like peptide-1 (GLP-1) can […]

This study will validate the accuracy of a new artificial intelligence (AI) powered application, which has been developed to track communication and cognition during the babbling stages of development in the first year of life. Once validated, this app will be an asset to both parents and clinicians. It will be used by parents and […]

This study will validate the accuracy of a new artificial intelligence (AI) powered application, which has been developed to track communication and cognition during the babbling stages of development in the first year of life. Once validated, this app will be an asset to both parents and clinicians. It will be used by parents and […]

The effectiveness of cancer drugs depends on several factors which are governed by the genetic and ‘epigenetic’ code of cancer cells. The epigenetic code comprises those heritable modifications that bookmark DNA and DNA-associated proteins to guide the expression of genetic attributes without changing the DNA sequence. This epigenetic code is written, read, and erased by […]

The effectiveness of cancer drugs depends on several factors which are governed by the genetic and ‘epigenetic’ code of cancer cells. The epigenetic code comprises those heritable modifications that bookmark DNA and DNA-associated proteins to guide the expression of genetic attributes without changing the DNA sequence. This epigenetic code is written, read, and erased by […]

This proposal aims to establish a collaborative research project between the City of Oshawa and the University of Toronto. It is part of the Teaching City Initiative. The immediate objective of this proposal is to use data collected over the last seven years to update pavement deterioration curves. The new dataset is larger (11700 data […]

Protein turnover is an incompletely understood aspect of biology, important for various processes including adaption to environmental stimuli. Over 500 protein complexes (E3 ligases) are involved in marking proteins for degradation, but only a small number of these E3 ligases are well characterised. The current project seeks to develop chemical inhibitors of GID4—a key component […]