Chemical targeting of HDAC6 as a strategy for anti-viral drug discovery

The emergence of viral pandemics, exemplified by the Coronavirus Disease (COVID-19), has exposed the urgent need for the development of viral infection therapeutics. In a short span of time, more than 1.5 million individuals have been infected and there have been nearly 90, 000 deaths worldwide. Our objective is to pharmacologically validate a new strategy […]

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WiFi Indoor Localization and Geofencing

Many mobile devices that are used in an enterprise are considered mission critical as they are heavily relied upon, allowing a worker to do their job. Locating these devices anywhere and anytime becomes that much more important, especially if they become lost or stolen. SOTI’s technology leverages GPS on a device to track its location […]

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SOTI SNAP Widget Enhancement

SOTI has developed a software product called SOTI SNAP that allows anyone to create an app with no programming or technical knowledge. SOTI SNAP allows users to create apps by dragging and dropping widgets onto a canvas and connecting them together to create an app. The research problem to be addressed is to solve customer […]

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SOTI SNAP Digital Signage

SOTI has developed a software product called SOTI SNAP that allows anyone to create an app with no programming or technical knowledge. The goal of this project is to develop media scheduler widgets so that users can create playlists consisting of mixed media (videos, images, documents) and then deploy them at specific hours on certain […]

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Detection and Characterization of the Synovium in Musculoskeletal Ultrasound

Arthritis is a chronic disease that severely decreases the quality of life and affects almost 4.6 million Canadians, costing $33 billion for the Canadian economy every year. Affected individuals experience pain and disability through an extended period of time. Rheumatoid arthritis (RA), a common form of arthritis, is an autoimmune disease characterized by the inflammation […]

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Detection for Smart Home Devices’ Environment with Neural Network

As smart home and artificial intelligence technologies are developing rapidly, smart home devices contribute to better living quality and safer spaces. These smart devices are intelligent agents. They receive a variety of signals through sensors placed in ecobee’s thermostats, light switches and other smart devices and controls the heating and cooling, lighting, as well as […]

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3D Conformal thermal therapy of the soft tissues for treatment of localized cancerusing MRI-controlled ultrasound therapy

MRI-guided ultrasound therapy is a powerful method of image-guided therapy for cancer treatment in which ultrasound energy is used to coagulate (or cook) a target region of tumor. This kind of treatment has been developed as an alternative to conventional therapies (radiation, surgery) which are associated with high complication rates and long recovery times. Successful […]

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The Development of Anti-gingivitis Probiotics Derived From the Human Oral Microbiome

The human oral cavity contains over 700 different bacterial species. In healthy people, these bacteria are living in harmony and not likely to cause diseases. However, sometimes this bacterial balance is disturbed as the oral pathogenic bacteria start to overgrow causing many oral implications such as halitosis, sore throat, dental caries and gingivitis. A promising […]

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Part 2 (extension): Long-term evaluation of corticosteroid-releasing formulations to suppress implant device- related foreign body reactions and fibrosis

Implanted medical devices have dramatically improved the lives of millions of patients worldwide. However, in many cases, the body’s immune system rejects these devices and encapsulates the implant in fibrous scar tissue. This reaction is most detrimental to sensors for continuous monitoring and treatment of chronic conditions such as diabetes and those of the central […]

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Auditory spatial and memory processing in the blind

Early loss of vision is accompanied by widespread cross-modal changes in the brain, in that ‘visual’ areas of the brain show responses to nonvisual stimuli. This raises the possibility of using the reorganization associated with vision loss to investigate how auditory events may be encoded and retrieved from memory. The proposed project will examine the […]

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Wine culture in Parthia and Gandhara: Rewriting the Classical Narrative on Dionysus in the East

My project aims primarily to understand cross-cultural interactions by investigating the visual and material culture pertaining to wine in Ancient Parthia (Iran/Syria) and Gandhara (Pakistan/Afghanistan) from the 2nd century BCE to the 2nd century CE. Art historical and archaeological scholarship on the topic has tended to focus on substantiating Classical influence on Eastern art in […]

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