Activity-based screening of DNA-Encoded libraries

Cell surface receptors are targets of ~50% of pharmaceutical and biological drugs. Still many of such receptors have no known therapeutic inhibitors because 1) the receptors are only active in cells 2) isolation and purification of the receptor is not viable and 3) determining activity of a potential therapeutic is complicated by binding that can […]

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Development of a Borehole Muon Detector for Muon Tomography

CRM Geotomography Technologies (CRM) has developed detectors that are able to measure cosmic ray muon particles underground. By measuring the rate at which these particles pass through the detectors, it is possible to reconstruct a three-dimensional map of the density of the earth’s subsurface above the detectors. This technique is called muon tomography. CRM’s detectors […]

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Low-cost Real-time Multi-constellation GNSS Precise Point Positioning for Intelligent Transportation System (ITS)

Intelligent Transportation System (ITS) enables smart traffic management and provides various innovative services including better safety, more road information, etc., which has drawn a lot of attention. The development of next-generation ITS services and applications must depend on more accurate positioning information at decimeter to even centimeter-level. Such capabilities are crucial because all of the […]

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Intelligent Product Quality Assessment (IPQA) Toolkit

Manufacturing is a main component driving the successful economy in a society. In order to remain competitive in the global manufacturing market, product quality control is critical. High quality product not only expands the client base, but also enables just-in-time correction to reduce the cost wasted in defective products. The goal of this project is […]

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Nanostructured cathode material for high performance all-solid-state sodium battery

Lithium batteries are almost universally integrated in modern electronics applications due to their high efficiency and scalability. However, the liquid lithium-ion electrolyte utilized in these batteries has a multitude of safety concerns including flammability, toxicity, and the ability to explode if short-circuited. These issues lead to problems while operating in hazardous environments, more stringent transportation […]

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Tagging and Auto-Captioning of Histopathology Scans for Diagnosis Assistance

Digital pathology uses modern scanners to capture high-resolution images from biopsy samples. Computer algorithms, especially artificial intelligence, can help in automatic searching for similar cases in the archive of hospitals and laboratories. Displaying similar images form the past patients, that have already been diagnosed and treated, can provide useful information to the pathologist to solidify […]

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Enhancing Nurses’ Role in Opioid Stewardship – Implications for health policy, practice advocacy) and patient safety – Year two

Multiple national strategies have been developed address the opioid crisis, however, Canada still remains the second largest consumer of prescription opioids. These drugs can have negative effects on consumers because they have addictive properties so therefore consumers may become addicted to these drugs if there are not taken as prescribed. For other drug classes such […]

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Zero-Emission Public Transit Fleet Systems – Year two

Electrification of transit vehicles is a part of Ontario’s long-term strategy to reduce transportation-related greenhouse gas (GHG) emissions. However, transit agencies and utility/local distribution companies face significant technological and operational hurdles in integrating “off the shelf” electric bus technologies. The postdoctoral fellow collaborating with Canadian Urban Transit Research & Innovation Consortium will work with transit […]

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