New therapeutics against T-cell acute lymphoblastic leukemia

A protein named c-Myc is causally implicated in over 50% of all human cancers. Preliminary work supports two proteins (POZ domain protein and c-Myc cofactor Miz-1) as a new drug target to disable c-Myc function. We have identified small molecules which act on this target and will now serve develop a series of optimized and […]

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Mucoadhesive nanoparticle eye drop drug delivery

Eye diseases, such as dry eye syndrome, affect about 15% of the population. Eye drop formulations are the most common way to treat eye diseases, but patients struggle with the multiple daily applications required and the resulting side effects. Our goal is to develop an eye drop formulation that requires less frequent application using nanoparticle […]

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