Multiplexed quantitative proteomics approaches to characterize residual host cell protein impurities in biopharmaceutical processing

Many drugs, such as those made of antibodies, are produced using cells from bacteria and other organisms. Companies such as BioVectra use this approach to produce antibody drugs efficiently and cost-effectively. At the end of the production process, residue such as protein from the “host” cells (called host cell proteins, or HCPs) must be removed […]

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