Synthesis of Fluorinated Cannabinoids

The recent legalization of marijuana has sparked renewed interest in studying the health benefits of the non-psychoactive cannabinoids. Cannabidiol (CBO, 1, Figure 1) has emerged as a promising medicinal candidate due to its potential for the treatment of anxiety, and chronic pain. In 2018, the first CBD-containing drug, Epidio1ex, was approved by the FDA for […]

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Computational Modelling of Cannabidiol Fluorination

Cannabidiol, is a non-intoxicating cannabinoid has anecdotal and preliminary evidence as a treatment for pain, anxiety, nausea and seizures. This project aims to identify the configuration of CBD when bound in the brain. We will use established computational techniques that have not been applied to CBD binding to calculate the pose that CBD adopts when […]

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