Intramucosal Lorazepam spray: Whole Cell and Extracellular Eelctrophysiological Study of Pharmacokinetics and Pharmacodynamics

Epileptic patients have a long term risk of recurrent seizures and the mainstay of treatment for controlling seizures is antiepileptic drugs. Management of epileptic emergencies usually requires hospitalization and the administration of intravenous (i.v.) anticonvulsant drugs. Lorazepam i.v. is the most effective treatment of status epilepticus, and therefore is routinely used in hospital emergency departments. […]

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