Cross cell type inference of TF binding by integrative analysis of TF ChIP-seq and chromatin accessibility profiles

Transcription factors (TF) are proteins that drive and maintain cellular functions by physically binding to DNA and regulating the expression levels of other genes. There are approximately 1,600 TFs in the human genome. Accurate and scalable identification of TF binding locations across the entire genome remains a major challenge. An effective solution to this problem […]

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