Development of the library of nanoparticle contrast probes for tissue clearing 3D microscopy compatible with multi-modal imaging in fluorescence, dark field, MRI, CT and electron microscopy modalities

High resolution 3D microscopy is a rapidly growing area of biomedical research, which has high potential to replace traditional 2D histology used for the analysis of tissue biopsies of cancer and other diseases. However, currently there is a limited availability of contrast agents that can label organs, biological tissues, and cells in a live animal […]

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Enzyme-free, one-step nucleic-acid detection for point-of-care COVID-19 diagnostic screening

Rapid diagnostic testing has proven essential for stemming the on-going COVID-19 pandemic. Given the global threat of COVID-19 transmission, millions of tests are needed per month to isolate infections and to facilitate safe reopening of societies. This internship will contribute to COVID-19 diagnosis efforts by first developing a faster and cost-effective protocol for viral nucleic-acid […]

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Development of nanoparticle in vivo labeling contrast probes for tissue clearing 3D microscopy compatible with multi-modal imaging in fluorescence, dark field, MRI, CT and electron microscopy modalities.

High resolution 3D microscopy in combination with tissue clearing techniques such as CLARITY, iDISCO, CUBIC is a rapidly growing area of biomedical research. It also has high potential to replace traditional 2D histology to become a method of choice for the analysis of tissue biopsy samples used in diagnosis of cancer and other diseases. However, […]

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