Evaluation of PLO Micelles for Transdermal Peptide Delivery to Superficial Bone

This research aims to develop and test a transdermal delivery system for small bone healing peptide hormones. Peptides and many drug molecules do not usually penetrate the outer skin barrier, the stratum corneum, in order to treat the underlying body tissues. However, by using liposomal gel as a drug delivery medium, it is often possible […]

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Transdermal delivery of peptide hormones to treat tibial bone stress fractures using DiffusiMax liposomal cream base

The goal of this Mitacs research proposal study is to develop and apply experimental methodology for transdermal delivery of bone-targeting peptide hormone drugs. We aim to deliver these compounds using an appropriate hydrophilic-hydrophobic Diffusimax liposomal drug delivery cream base to anatomically superficial bone, at the sites of stress fractures (also known as “shin-splints”) in order […]

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