Quantifying the oxidization of polysaccharides and optimizing dextran-bovine serum albumin glycation conditions for development of a new pneumococcal vaccine

Pneumonia remains the single leading cause of childhood death under age 5 worldwide. The price per dose of current vaccines is high and supply is limited due to a complex manufacturing process and low yield, significantly reducing its distribution in developing nations. A newly patented vacuo dry-glycation process promises much higher efficacy than the conjugation […]

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In Vacuo Glycation of Insulin

More than 2 million Canadians suffer from diabetes, a disease associated with the body’s inability to produce or effectively use insulin. The high blood sugar levels associated with diabetes can lead to serious complications such as vision loss, kidney failure, cardiovascular problems, and amputation. Therefore, diabetes patients are treated with insulin, with the aim of […]

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Investigating polysaccharide-protein conjugation: characterization and effects of glycation conditions

Pneumonia remains the single leading cause of childhood death under age 5 worldwide. The price per dose of current vaccines is high and supply is limited due to a complex manufacturing process and low yield, significantly reducing its distribution in developing nations.1 A newly patented vacuo dry-glycation process promises much higher efficacy than the conjugation […]

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