Chemotherapy drugs target and kill rapidly-dividing cells located closest to blood vessels, but do not penetrate deep into the tumor. Limited drug distribution in tumors is an important cause of drug resistance. A method to increase tumor drug delivery and combat resistance is the subject of this proposal. To counteract chemotherapy resistance, the use of […]

Vaccination is an important preventive measure against influenza infection during both seasonal epidemics and pandemic outbreaks. This research aims to evaluate the health benefits and costs associated with a new vaccine developed by Sanofi for seasonal influenza. This vaccine provides better efficacy and higher protection for individuals over 65 years of age. The vaccine is […]

Manufacturing of consistently high quality products is the commitment of the pharmaceutical industry. To achieve this, new products must be thoroughly tested and the results must meet government-approved product specifications. Improving existing and adopting improved analytical technologies for product testing ensure the production of safe and effective products. This is particularly critical for the manufacturing […]

Heterogeneity of cell populations is a common occurrence in bioreactor operations (Lara et al., 2006) and is typically caused by processing of cell cultures in vessels of varying sizes and process conditions and by deficient mixing. Most bioreactor research deals with average conditions of the cell population with respect to quantities such as dissolved oxygen […]