Preclinical evaluation of novel meningococcal vaccines

Neisseria meningitidis (Nme) is a bacterial pathogen that often colonizes the upper respiratory tract of humans without symptoms, but which may also develop into rapidly-progressing sepsis and meningitis that can be fatal. Nme has evolved elegant means to specifically interact with human cells and proteins in order to colonize, survive and the evade host immune […]

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Understanding the scope for innovations in vaccine technology in the swine industry

Pig production is a vital component of the Canadian agricultural sector. Airborne bacterial pathogens Haemophilus parasuis, Actinobacillus pleuropneumoniae and Actinobacillus suis are major causes of swine respiratory disease and cause rapidly progressing systemic infections that lead to significant morbidity and mortality. We are developing engineered subunit vaccines that can simultaneously target all three pathogens and […]

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