Preclinical development of long-acting injectable antibiotic gels for the pharmacotherapy of drug-resistant tuberculosis

The project was initiated to tackle the public health crisis posed by the emergence of multidrug-resistant tuberculosis (MDR-TB), which is more challenging to treat than drug-sensitive TB and typically requires longer treatment regimens (i.e., > 18 months). Treating MDR-TB involves daily medication usage (either as oral tablets, capsules, liquids or injections) making adherence to treatment […]

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Applications of Homological Algebra to Toplogical Data Analysis

The use of large data sets in today’s world necessitates robust methods for classifying data. Topological data analysis (TDA) studies the shape of data collected in a geometric space. It has been applied to numerous data analysis problems, from glass manufacturing to cancer research. TDA involves examining the data at different distances. TDA constructs a […]

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Robotic Assistance for Soft Tissue Surgery

Cooperative robotics in soft tissue surgery represents an innovative approach aimed at improving surgical precision, control, and safety. Soft tissue procedures are challenging due to the delicate, deformable nature of tissues and the close proximity to critical structures, requiring exceptional accuracy to avoid complications. Cooperative robotic systems are designed to work directly alongside surgeons, amplifying […]

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Modeling and Simulation of Novel Bioplastics Materials with Natural Fibers

This collaborative project, involving the University of Saskatchewan and Université de Lorraine in France, seeks to advance our understanding of bioplastics—environmentally-friendly materials made by combining polymers with natural fibers like flax or hemp. Our aim is to develop models that can predict how these materials behave under different conditions. By studying the small-scale structures of […]

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The Effects of Sex Differences on Acute Muscle Protein Synthesis Responses following High-Intensity Interval Training

Musculoskeletal conditions, such as sarcopenia and frailty, have been documented to affect over one billion individuals globally. To address the escalating issues of muscle atrophy, resistance training (RE) has been widely recognized for preserving and enhancing muscle mass. However, individuals nowadays often face time constraints, making it challenging to consistently engage in RE. Considering this, […]

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Japan Society for the Promotion of Science

This study is part of a larger project on gender and national security based on cross-country comparisons of feminist national security, led by Dr. Veronica Kitchen (University of Waterloo) and Dr. Tanya Narozhna (University of Winnipeg). It aims to explore Japan’s approach to pursuing feminist foreign policies and identifying areas where national security can incorporate […]

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Simple Receptor Protein Generation

Receptor proteins are important for therapeutics, medicines, diagnostics and biomanufacturing. Generating new proteins is incredibly difficult however machine learning techniques have been developed to assist in evolving proteins. Using these techniques, I plan to create receptor mimics that are smaller and have improved properties. These will benefit many industries such as therapeutics, medicines, diagnostics and […]

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Validating chemical candidates for axon regeneration in the rodent visual system

Neurons are like electrical wires that help the brain communicate with itself and other parts of the body. If broken, this ability is impaired, leading to reduced sensation and or motor function. Neurons in the mature mammalian central nervous system (CNS) don’t grow back after injury due to cellular, biochemical and physical barriers. Currently, there […]

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Ranking Elements of Realism of VR Avatars

In (VR, we can’t see our bodies due to replacing the real world with a virtual one. This leads to disembodiment, which has been shown to impact performance. An avatar, a digital body, can create that embodiment. The proposed research aims to combine the topic of the intern’s master’s thesis, “Investigating Graphical Realism in Mixed […]

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The Politics of Consent in United Nations Peace Operations

My research explores a key challenge in United Nations (UN) peace operations: maintaining reliable consent from host countries. Consent from the host government is crucial for the UN to operate effectively, but this support often fluctuates. Some countries initially welcome UN missions but later restrict their activities or withdraw consent, which can disrupt peace efforts […]

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Uncovering genetic interactions of the translesion synthesis pathway: targeting DNA repair mechanisms as a therapeutic strategy in cancer

This project investigates how different genes involved in DNA repair work together to keep cancer cells alive. We’re focusing on a specific process called translesion synthesis (TLS), which helps cells bypass damage in their DNA. By understanding these genetic interactions, we hope to identify new ways to target and kill cancer cells, especially those that […]

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