Les enzymes dihydrofolate réductases de type B (DfrB), identifiées pour la première fois dans les années 1970, confèrent une forte résistance à l’antibiotique triméthoprime. Depuis, ces enzymes ont été étudiées en détail de manière enzymatique et biophysique. Alors que ces enzymes sont connues depuis cinquante ans, leur origine évolutive demeure un mystère. Ainsi, cette recherche […]

L’année 2021 est marquée par un accroissement significatif des tensions dans la relation entre la France et le Royaume-Uni. Les confrontations entre le président Macron et le premier ministre Johnson se sont accumulés, allant de mal en pis. Pourtant, la relation franco-britannique en matière de défense et de sécurité se porte particulièrement bien depuis les […]

In light of an urgent ecological demand for attentiveness to the non-human; outcomes. this proposal stresses the importance of the literary medium in addressing eco-critical questions. In essence, this project explores the interdependency of human and non-human entities through literary-material desires: collecting, hoarding, and discarding. My research thus asks how we can read literature under […]

Neurons situated in a brain region called the hippocampus have been discovered to represent information related to numerous aspects of space and navigation. The activity of these neurons is referred to as the cognitive map, a complex brain representation of space, navigation and other associated physical clues. The aim of this project is to design, […]

In modern kraft pulp mills, the kraft recovery boiler can produce all the steam and electricity needed for the mill and even sell green electricity to the grid. However, most mills still have the fossil CO2 emissions from the combustion of fossil fuels in lime kilns. For mills to eliminate this source of fossil CO2, […]

In this project I will develop a computational framework for the automatic detection of task-related biomarkers in PD patients during speech production. This framework will help us to predict the timing of electrical stimulation in STN with the purpose of understanding the role of STN in encoding different aspects of speech production. To achieve this […]

When stars like our Sun reach the end of their lives, they become giants and eject a lot of their initial mass through a slow, dense outflow. These winds are driven by microscopic solid particles (dust grains) that condense in the cool stellar atmospheres. The dust is the product of a large number of chemical […]

Given a group of molecules and a specification of reaction conditions, do chemical reactions occur? If so, what products are produced, and what is their relative abundance? This problem pervades chemistry, with applications in environmental science (e.g., the degradation of pollutants), molecular sensing (e.g., interpreting the results of tandem mass spectrometry), chemical synthesis (e.g., finding […]

Outdoor winter sport athletes face unique weather conditions that might include wind, snow and rain. These weather conditions can occur at a variety of air temperatures, ranging from above zero to -20 C. The colder the air temperature the more challenges winter sport athletes face in warming up for competition and then staying warm. The […]

The GSI projectile fragment separator (FRS) is a versatile, high-resolution magnetic spectrometer designed to efficiently separate projectile fragments in their mass and nuclear charge. It has been efficiently used in the study of nuclear structure and reaction dynamics with relativistic radioactive heavy-ions over the last few decades. In the present project the intern will learn […]

The student will use the interacting shell model to study properties of ground and low-lying excited states as well as the corresponding electromagnetic and weak transitions for nuclei of importance for astrophysical scenarios like the nucleosynthesis in the r-process. For this the student has to learn about the shell model and how to perform and […]

Avec le développement en parallèle de technologies de traitement automatique des langues de plus en plus performantes, de théories linguistiques de plus en plus précises et de banque de données de plus en plus riches, il est maintenant plus facile de comparer les langues et d’identifier leurs points communs et leurs divergences. Un défi pour […]