Collective dynamics of interacting cells during development

Multicellular organisms begin as a single cell with instructions encoded by the genome. During development this cell multiplies many times generating an enormous number of cells, each with its own specialized role. For example, developed humans are composed of trillions of cells but our organs and limbs have the right form, location, and function with […]

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Modélisation personnalisée de l’articulation thoraco-scapulo-humérale pour l’aide au diagnostic et au traitement

Des douleurs ou pertes de mobilité associées à l’épaule peuvent rapidement se révéler handicapante dans la vie quotidienne. Une meilleure compréhension des mécanismes de l’épaule pourrait aboutir à une meilleure prise en charge des patients présentant des symptômes handicapants. La modélisation 3D de l’épaule en prenant en compte la posture du patient en routine clinique […]

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New Wearable Headbands for Sleep Assessment

The standard approach to quantifying sleep physiology, polysomnography, requires an overnight stay in the laboratory, is poorly tolerated by many people (especially the elderly or those with medical co-morbidities) and is both labour intensive and costly. In response to this limitation, wearable devices have gained support as tools for self-administered measurement of some aspects of […]

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Development of a 3D environment for ventricular puncture

Ventricular drainage is commonly performed in neurosurgery departments or in theemergency room. It consists of inserting a catheter into the brain, using a needle, until it reaches the frontal horn to drain cerebrospinal fluid for therapeutic or diagnostic purposes. Nowadays, the learning of this gesture is only performed by companionship: there is no effective simulator […]

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Impact of industrial whaling: scale, ecological, and evolutionary legacies

The large baleen whales were driven to near-extinction by industrial whaling during the 16th–20th centuries. Several key questions remain about the effects of this large-scale removal, such as: (a) what were the abundances of pre-whaling populations; (b) did whaling and subsequent recovery lead to changes in population structure, and connectivity; and (c) did the extreme […]

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Low Hopes, Bad Democracy? A Tale of Unexpected Winners and Losers

A great amount of research has noted the existence of a gap between winners and losers in relation to satisfaction with democracy (SWD). As stated by Craig et al. (2006, 579), “winners and losers do not always respond with equal enthusiasm either to the election outcome, or to the institutions and processes through which that […]

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HIV infection and fertility among adolescent girls in sub-Saharan Africa

Adolescent girls in sub-Saharan Africa are the population group with the highest level of unmet sexual and reproductive health needs worldwide. Early onset of sexual activity is associated with a double burden of HIV infection and pregnancy. However, so far both problems have been analyzed as independent events. My objective is to examine fertility patterns […]

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Neuroinflammation in Huntington’s Disease

Huntington’s disease (HD) is a genetic neurodegenerative disease characterized by cognitive, motor, and psychiatric disturbance ending in death 15 to 20 years after the onset of the first symptoms. The genetic predictability of HD makes it potentially the most tractable of the neurodegenerative diseases for early intervention, with the optimum time for the introduction of […]

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In vitro effects of high irradiance delivered by laser and polywave light-curing units on the simulated pulp temperature rise and mechanical properties of bulk-fill resin composites

Dental light-curing units (LCUs) are used every day in most dental offices. If this LCU is misused, this dental work can fail prematurely causing pain, post-operative sensitivity, pulpal death, and economic hardship. In Canada, dental curing lights are Class 1 medical devices, and Health Canada does not test dental curing lights before they are used […]

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Functional and structural characterization of clinically relevant amyloid fibrils

Irreversible, progressive, and incurable neurodegenerative diseases, such as Alzheimer’s disease (AD) or Parkinson’s disease (PD), constitute severe challenges for the modern and, in particular, for the healthcare system. Recent reports suggest that worldwide >50 Mio. people and >10 Mio. people are living with AD or PD, respectively. Both diseases are related to protein misfolding and […]

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Changes in soil nitrogen dynamics and crop growth by biochar and nitrification inhibitor as investigated by carbon and nitrogen isotope ratios

Cropland soils are important sources of nitrous oxide (N2O), which is one of greenhouse gases. In soils, N2O is produced through nitrification and denitrification processes. Therefore, it may be possible to reduce N2O production by using biochar and nitrification inhibitors (NI). Biochar is known to decrease N2O production through biological and physico-chemical interaction with soil […]

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Development of a conceptual design for a recoil separator to study radiative neutron capture reaction using a low energy ion storage ring

TRIUMF has begun the TRISR project constructing a experimental facility which is called low energy ion storage ring. The storage ring will provide unique possibilities for investigations of nuclear reactions when it is connected to a radioactive ion beam facility ISAC-I of TRIUMF. A neutron generator will be added to the facility to provide a […]

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