Design and validation of a novel peptide immunotherapeutic for the treatment of dog allergies

Adiga Life Sciences Inc. developed a novel immunotherapeutic platform in which small components (peptides) of allergen proteins are identified and administered in a regimen that causes immune cells to become non-responsive towards the allergens. In a phase II clinical trial, the cat allergy treatment developed by Adiga using this platform reduced allergic symptoms in allergic […]

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Design and validation of a novel peptide immunotherapeutic for the treatment of dog allergies – Year two

Adiga Life Sciences Inc. developed a novel immunotherapeutic platform in which small components (peptides) of allergen proteins are identified and administered in a regimen that causes immune cells to become non-responsive towards the allergens. In a phase II clinical trial, the cat allergy treatment developed by Adiga using this platform reduced allergic symptoms in allergic […]

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Leader competencies and character: A novel approach to leader development

Historically, executive coaching programs have focused on developing a leader’s competencies. More recently, the character of leaders has received increased attention in the media and in research literature. This can be attributed to the financial crisis of 2008-2009, which shined a spotlight on unethical decision-making by leaders in organizations. As a result, there is a […]

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3-D UAV Magnetometry for Improved Target Characterization in Mineral Exploration

Geophysical exploration is one of the primary forms of preliminary site investigation used to characterize ore potential and the economic viability of newly discovered mineral deposits. The current platforms for collecting magnetic data include dense coverage but low resolution airborne surveys and high resolution but low coverage terrestrial surveys. The recent proliferation of Unmanned Aerial […]

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Feasibility Evaluation Study of LifeguardMobile (designed for supported self-management of patients with chronic and complex conditions)

“Lifeguard Health Networks Inc. (LHN) has developed a secure Virtual Health Assistant application (app), to enhance supported self-management for patients with chronic and complex conditions, by leveraging their network of trusted family and friends, under the direction and guidance of health practitioners.We are conducting a study to evaluate the feasibility of the app and the […]

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Evaluating heterogeneous enterprise content environments: a case study of control

This research seeks to address common issues that plague content and information management at small to medium–sized, knowledge–intensive enterprises. By using qualitative research methods and drawing on a theory of control this case study will provide specific, practical, and usable information about inefficiencies and pain points experienced by Algorithmics, in addition to enriching the trade […]

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A Framework for Creating and Managing Virtual Organizations in a Distributed Environment Using SOA Infrastructure

In this research, we propose a framework to create and manage virtual organizations (VO) in a distributed environment based on service oriented infrastructure. The proposed framework enables networks of organizations to form virtual workflows based on their software infrastructures, and share and monitor their performance metrics without the need for a central authority. An abstraction […]

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CryoVent – Low or zero carbon cryogenic ventilation for deep mines

The main purpose of this research project is to integrate wind power with cryogen production, which could be one of the most low-carbon and economic methods to generate and store energy. As it can be transported and stored relatively easily, the cryogen becomes an energy vector, like a fuel, that can be used to transport […]

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Simulating heat transfer mechanisms for additive manufacturing processes

Additive manufacturing (AM) is a process family which is widely used for deposition of thin protective layers of novel alloy materials on components operating in severe conditions, and also for fabrication and repair of complex 3D parts. The scope of this research is to establish a process planning framework for metal based bead deposition processes […]

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Development of a numerical wave uprush prediction tool for the Cataraqui Region Conservation Authority Lake Ontario and St. Lawrence River shoreline

Wave uprush and the potential for flooding are natural hazards that must be determined by the Cataraqui Region Conservation Authority (CRCA) prior to the approval of a near-shore development. The purpose of calculating wave uprush is to recommend building sites that are outside of the wave uprush area (and floodplain in general) to land owners […]

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Optimization of Digital Pathology Storage and Retrieval Strategy

One of the major obstacles that hinders the adaption of the digital pathology solutions is the inadequate performance and network overload for pathology image storage and retrieval. A common technical problem is the limited bandwidth of the network and the delayed transmission speed of digital images to the viewing station. There is an urgent need […]

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Modeling and Analysis of access-control policies (SELinux and/or SMACK)

Access-control policy management is an increasingly hard problem from both the security point of view (is the policy “safe”?) and the functionality point of view (does the system still work as expected?). Even when a policy is considered both safe and functional, each addition, deletion or modification of the policy has the potential to break […]

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