Many patients who initially respond well to highly efficacious chemotherapy eventually develop resistance and relapse despite continued treatment. These cancers acquire drug resistance to current therapies through various mechanisms such as the acquisition of mutations for example. Furthermore, some promising targets that play a crucial role in the progression of cancer have been deemed undruggable […]

The automotive industry has recognized electric bike use as an integral part of the urban mobility of the future. To promote mass adoption of the integration of electric bikes with cars, the user perception of safety has to be improved. The objective of the proposed study is to investigate how aerodynamics and anxiety levels of […]

Many new pharmaceuticals are based on large biomolecules like proteins. Even small differences in the protein structure can cause significant changes in the efficacy and safety of these drugs. Furthermore, these large molecules are difficult to characterize without advanced instrumentation and methods. Current technologies still struggle with robustness and reproducibility. This study aims to introduce […]

This project will use a low energy particle accelerator to explore methods of improving the number of fusion reactions in specially designed targets. This work will then be used assist in the development of a feasible commercial fusion power plant that is green, uses cheap and abundant fuel, and is reliable.

Research into child safety applications using Artificial Intelligence (AI) methods is a new area of investigation. SafeToNet is continuing to develop AI monitoring tools together with a team of researchers at the University of Ottawa. These tools, when used over time, will take advantage of outgoing text-based communications from devices to detect the early onset […]

Solids exist as crystals, amorphous or subcooled liquids. The degree of crystallinity determines the long range order in a solid phase. Molecules when transferred from the solution to the solid phase may take many different crystal forms (polymorphs, solvates/hydrates, salts, co-crystals). Theoretically, there are 230 space groups describing the diversity of a crystalline material. About […]

Helicobacter pylori (HP) is a bacterium that causes 65% of gastric ulcers and cancers worldwide. Current anti HP treatments often fail because the bacteria have become resistant and they have serious side effects. We are looking into using molecules produced by bacteria called Lactobacilli that are a natural component of the human gastro-intestinal flora to […]

Several classes of psychotropic compounds have been increasingly shown to possess antimicrobial properties with possible implication in microbiota-gut-brain axis. For instance, sertraline and paroxetine are efflux inhibitors in bacteria cell walls and are effective on gram-positive bacteria such as Enterococcus and Staphylococcus. Therefore, a comprehensive assessment of the antimicrobial effect of these chemicals on gut […]

The Northeast Pickering land holding was acquired with the intention of developing an innovative and environmentally conscious community. The proposed undertaking intends to implement low impact development features which manage rainwater where it falls. This rainwater management approach is an environmentally sustainable alternative to the common practice of routing rainwater through curbs and pipes to […]

Life on the planet has evolved in constant presence of radiation, some of which comes from space, and some of which comes from natural sources in the Earth. This natural background radiation (NBR) is a normal component of biological life. One way we can study the role of NBR in life is to see what […]

Cannabis has been known to treat ailments for thousands of years, including conditions such as pain, cancer, arthritis, glaucoma, multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS). Despite an increase in research dedicated to molecular and behavioural effects of cannabinoids, there has been no direct evidence to elucidate the effect of cannabis on pain-related areas […]

Slave labour continues to be used in business settings around the world and is often linked to society through the supply chains for consumer goods. Yet, the issue of slavery in modern society (“modern slavery”), despite its ties to business settings, has received very little attention in societies around the around. While countries such as […]