This project focuses on improving how we detect Alzheimer’s disease early by measuring lesser-known, protective forms of the amyloid-ß protein—Aß34, Aß37, and Aß38—in blood and cerebrospinal fluid. These shorter forms are thought to help clear the harmful ones that build up in the brain and cause damage. Using a highly sensitive method called single molecule […]

We are extremely excited about the collaboration between three leading research institutes-Lakehead University, KTH and RISE- driving innovation, skill development and shared expertise, all focused on transforming waste into value added products. We are pioneering a new approach for applying lignin, a biobased material in formulating a biodegradable, green and sustainable emulsifier. Lignin is a […]

The Healthcare Kiosk Project aims to enhance access to timely medical care by deploying self-service, automated kiosks that enable patients to conduct virtual doctor consultations, perform basic blood tests, and collect blood samples for laboratory analysis—all without the need for an appointment. By placing these kiosks in accessible locations such as pharmacies, hospitals, and walk-in […]

VerteVUE is a portable, radiation free, imaging device that will allow clinicians to assess critical anatomical features of the spine at the point of care. VerteVUE supports early clinical decision making when used alongside patient reported outcome measures (PROMs), standardized questionnaires and physical assessments. It also streamlines triage to determine conservative versus surgical care, reducing […]

Prostate cancer is the most common male cancer in Canada. While many patients live long lives with treatment, some develop incurable disease that spreads to the bones. When this happens, survival drops sharply and patients often face severe pain, broken bones, and serious complications such as spinal cord damage. Bone changes caused by prostate cancer […]

Surfactant Protein B (SPB) deficiency is a rare genetic disease where surfactant B is not produced in the lung, proper breathing fails and lungs collapse. The disease usually presents early in life, and unless lung transplantation is performed, no other approaches have provided long-term cure. Yet, lung transplantation is not an ideal approach either, as […]

The project’s goal is to investigate the use of a 2D reduced graphene oxide (rGO) based microfluidic channel driven electrochemical biosensor to detect AMI biomarkers. The device could be able to identify heart attacks before they happen. Therefore, it may be beneficial to reduce the enormous number of deaths brought on by this illness worldwide. […]

mRNA vaccine technologies came to the forefront of public health during the recent global pandemic and this technology also has great potential for other therapeutic approaches. These vaccine platforms require that the mRNA be encapsulated by fat molecules into structures called “lipid nanoparticles”, and the specific chemical formulations of the mRNA and fats determine the […]

Nucleic acids such as DNA and RNA offer exceptional opportunities to fight against infectious and genetic diseases. To use nucleic acids effectively in a clinical setting, one needs to use effective delivery vehicles that can deliver the nucleic acids into the diseased cells. This project will develop effective delivery systems for this purpose. The delivery […]

Dairy fermented products receive a lot of attention from consumers. An issue of dairy fermented foods, especially cheese, is a potential development of bitter taste. A main protein in milk is casein proteins. This family of proteins contains much higher contents of proline, which shows very bitter taste in its peptide forms. During fermentation, casein […]

The hormone insulin rises in the blood after consuming food. Too high of an insulin response may be a sign of dysfunctional metabolism and has also been shown to promote weight gain. Thus, if insulin levels rise too high after a meal it may indicate that someone is metabolically unhealthy or is prone to obesity. […]

Kane Biotech Inc. is a Manitoba based company that provides innovative technologies that breakdown and disperse microbial biofilms. Dispersin B is an enzyme that both inhibits and disperses bacterial biofilms. Kane Biotech Inc. has expressed this enzyme protein in E. coli, with the goal of developing Dispersin B based products. Dispersin B yield and cost […]