iSpine: A Innovative Spine Image ProcessingToolkit

A versatile spine modeling toolkit would enable the automatic assessment of gross anomalies and the evaluation of limited regions and spine components such as vertebra and discs. The system would consist of modules for: 1) segmenting the spine; 2) modeling spinal components; 3) detecting, assessing and analyzing salient features; and 4) generating information for medical […]

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Provincial Health Authority: Organizational Transition

There are no shortage of news stories concerning the challenges in the healthcare system. These include covid impacts, financial challenges, human resource challenges related to recruitment, burnout and retention, as well as the need for the system to operate more efficiently (see https://www.cma.ca/news-releases-and-statements/canadas-health-system-life-support-health-workers-call-urgent ; https://www.macleans.ca/society/health/our-current-health-care-disaster-could-have-been-averted/ ). Provinces often devote up to 40% of their budgets […]

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Exploring Toxoplasma gondii virulence using quantitative proteomics

Toxoplasma gondii is a pathogen of cats that can infect a wide variety of species including humans and sheep. Although there is only one species of T. gondii, there are many strains of the parasite with varying degrees of severity resulting in different disease outcome. When a human or animal is infected, the host may […]

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Generation of synthetic images of chest radiography with chronic obstructive pulmonary disease using artificial intelligence techniques

The main purpose of this research is to propose a strategy to generate synthetic chest x-ray images from data of clinical interest. The generated images should visually reproduce lung disease based on the selected input characteristics. This requires the processing and analysis of images using algorithms that identify the most relevant characteristics and variables to […]

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Assessment of life cycle environmental and economic sustainability of kidney care services: A case study of British Columbia

Climate change is one of the greatest threats to human health in the 21st century, with approximately one in four worldwide, attributable to environmental factors (1). Ironically, healthcare itself is responsible for 5% of annual global greenhouse gas (GHG) emissions, equivalent to airplane travel (2). Within healthcare, kidney care services have substantial environmental impacts compared […]

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The cellular-molecular landscape of the living human hippocampus

The human brain consists of more than 100 billion cells, many with specific structures and functions, performing complicated computations every day. Understanding these properties is a key component for the development of therapies for neurological disorders such as epilepsy, depression and brain tumours. So far, most of our knowledge of the human brain has been […]

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Application of deep learning generative network algorithms linked with super-resolution methods and fusion techniques to improve the quality of noisy and unlabeled ultrasound images

We aim at developing new approaches which have not been performed so far, such as i) enhancing the resolution and quality of noisy and unlabeled conventional ultrasound images through deep learning SRMs, ii) synthesizing high-quality MRI from the enhanced ultrasound images through generative networks, iii) fusing ultrasound and synthetic MRI images for different aspects such […]

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La science des données au service des athlètes olympiques canadiennes de water polo : développement de profils de performance

Ce projet proposé par l’Institut national du sport du Québec (INS Québec), en collaboration avec l’équipe nationale féminine de Water Polo Canada, a comme principal objectif d’exploiter les données d’entraînement, de tests physiques et les résultats de compétition, collectés au cours des 10 dernières années, auprès de 202 athlètes. Nous exploiterons les modèles et techniques […]

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Epilepsy Pre-Evaluation Space (EPES)

The aim of the EPES (Epilepsy Pre-Evaluation Space) is to create an immersive tool to better understand spatiotemporal phenomena inside epilepsy patients’ brains, by creating a 4D spatial-temporal visualization of electrical activity. Used for pre-surgical evaluation of epilepsy patients suited for surgical resection of the brain region, where seizures onset zone lies. EPES provides an […]

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EarlyDetect, a cloud based mental health screening tool – phase 2

The Chokka Center for Integrative Health is dedicated to develop an innovative and integrative approach to help patients achieve optimal mental health. Mental illness is the leading cause of disability in the world. Diagnosing mental health syndromes have proved challenging for clinicians. But it is essential to screen and diagnosis early to achieve symptom remission […]

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Radiochemistry for the Pharmacokinetic Evaluation of Novel Bone-Targeting Peptide Hormone Derivatives Year Two

This proposed research project is about development of new bone-targeting drug called PTHPEG- BP, this new compound will overcome shortages of current clinical peptide hormone PTH, and show better treatment efficacy and lower price then the latter; several new technologies will be used on research of this PTH, such as micro Positron Emission Tomography (PET/CT), […]

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