Tissue-constructs to predict optimal vaccine response in neonates.

Vaccines are one of the most effective methods for protection against life-threatening infections such as hepatitis B. Due to the difficulties associated with extensive clinical trials on younger population groups such as infants and newborns, vaccine research is primarily conducted on adults. Therefore, there is a significant gap in our current knowledge of early-life immune mechanisms. In this study, we will use an innovative technique that utilizes blood samples retrieved during a newborn’s birth to measure different biological information, including genes and proteins, to predict and understand the vaccine response of newborns. The findings from this study will provide new insights to improve the immunization protocols adopted by health organizations across the world, furthering the goals of our partner organization, PROOF Centre of Excellence.

Faculty Supervisor:

Scott J. Tebbutt

Student:

Partner:

PROOF Centre of Excellence

Discipline:

Life Sciences

Sector:

Health and Related Sciences & Technology; Professional, scientific and technical services

University:

The University of British Columbia

Program: