A critical challenge today in neuro-surgery is the determination of tumor boundaries intraoperatively. There are means of doing this using high-resolution MRI machines, however, these can be prohibitively costly. Optical coherence tomography (OCT) offers a promising, cheaper, label-free alternative. However, the basic models used for clinical, real-time OCT limit its usefulness and depth of focus. […]

Pathologic changes that occur in the cervical spinal cord as a result of injury and disease are not well characterized with current clinical imaging techniques. Synaptive Medical has recently developed a suite of innovative medical imaging products focused on the brain and image-guided neurosurgery. They are interested in investigating the potential application of these technologies […]

Copy number variations (CNVs) are an important type of structural variation affecting pathogenesis of complex diseases, such as inflammatory bowel disease (IBD). Accurate detection of genomic regions with CNVs is crucial for understanding the etiology of IBD, as these regions contain likely drivers of disease development. Microarray technology provides single-nucleotide resolution genomic data and is […]

Infectious diseases ranging from avian influenza to Ebola virus infection are among the most serious health emergencies in Canada and globally. Current diagnosis methods such as cell culture, ELISA and PCR suffer from inaccuracy, high-cost and lengthy procedures. Therefore, there has been a growing trend to develop new point-of-care diagnostic tools and microfluidic devices are […]

The Think-Move-Play project’s purpose is to study the feasibility and acceptability of utilizing smart insoles to collect health information and interact with patients suffering from hip fracture and neurological diseases. We propose a unique solution by combining personal health monitoring and coaching that is augmented with a virtual play environment aimed to maintain constant high […]

One of the major obstacles that hinders the adaption of the digital pathology solutions is the inadequate performance and network overload for pathology image storage and retrieval. A common technical problem is the limited bandwidth of the network and the delayed transmission speed of digital images to the viewing station. There is an urgent need […]

Approximately 1.7 million people sustain head injuries each year in the United States alone with associated costs exceeding $60 billion. One of the most common symptoms of a head injury is decreased postural control that may be associated with changes in heart rate and blood pressure which may lead to syncope (fainting) , pre-syncope, or […]

The impact of frailty on the ultimate functional recovery, independence, and quality of life among elderly patients undergoing cardiac surgery is not known. This study was done to explore the association between frailty and cardiac surgery outcomes. We will investigate independent living status and health-related quality of life (HR-QoL) in frail, elderly patients undergoing cardiac […]

Les hôpitaux et autres établissements de la santé font faces à des problèmes de planification et d’ordonnancement du personnel. Les travaux recensés mettent davantage l’emphase sur la confection des horaires de travail des infirmières et auxiliaires que sur la création d’horaires des médecins. Plusieurs outils issus du domaine industriel ont été utilisés et adaptés au […]

Alzheimer’s disease (AD) is a major challenge for the individual affected, society at large and there only modest effective drug treatment. We believe that a central problem in AD is the deteriorating fuel supply to the brain (mostly the sugar, glucose) and this impairment appears long before the onset of memory and cognitive problems emerge. […]

The research project will assist the Ottawa Branch of the Canadian Mental Health Association (CMHA-Ottawa) with the evaluation of new innovative mental health services intended to divert individuals from their overuse of emergency rooms and having further hospitalizations for mental health problems. The project will involve three separate studies over a two-year period: (1) an […]

bc211 is a non-profit organization that seeks to change its business model in the face of decreasing availability of traditional funding sources and increasing demand for its services. The research project will identify and assess various alternatives in which dual objectives can be met. Using mixed methods approaches and financial planning tools, this project will […]