Breeding for powdery mildew resistance in medical and recreational Cannabis sativa: strategies- to improve resistance

Powdery mildew is a foliar fungal disease that attacks all Cannabis sativa varieties. The majority of license producers (LP) producers have witnessed evidence of this problem firsthand. Plant yields and ultimate profitability can be severely undermined by pathogen infections. This pathogen is challenging to deal with, and early detection of fungus and pests eliminate these […]

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Somatic cell reprogramming as a tool for the conservation of genetic resources from endangered species

Conservation of endangered species has become increasingly urgent. This is evident given the rate of species extinction has increased by 100 to 1000-fold, and global biodiversity has decreased. With current climatic changes, these concerns will only grow. Assisted reproductive technologies can play a vital role in endangered species conservation. Many approaches are currently being utilized […]

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Dissecting fibroblast-macrophage-T-regulatory cell communication in the fibrotic niche

Idiopathic pulmonary (lung) fibrosis (IPF) affects 5 million people with a mean survival time of 2-3 years after diagnosis. In lung fibrosis, connective tissue fibroblasts excessively produce and stiffen collagen matrix. The resulting scar destroys the delicate lung architecture, decreases lung compliance and gas exchange, ultimately rendering patients unable to breathe. The only effective treatment […]

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Characterization and quantification of adsorbed antigens in adjuvanted vaccines

Vaccines are one of the most important medical breakthroughs, proactively saving millions of lifes and reducing human morbidity. Yet there remains a need to make current vaccine formulations more effective and affordable, which requires testing and optimizing new formulations. In addition, there remains diseases for which there are no efficient vaccine. To develop and test […]

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Anthropogenic impacts on the population dynamics of a critically endangered marine mammal

Economic development often has dire consequences for wildlife and environmental conservation. In Taiwan coastal waters, a small dolphin population is being affected by large-scale habitat loss and degradation resulting from development projects, pollution, vessel traffic and a massive fishing industry. The research aims to identify the threats having the greatest impacts on different aspects of […]

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Development of a Diagnostic Screening Platform for Quantitative Detection of Drugs in Saliva

Drug-impaired driving represents a significant and increasing threat to the safety of Canadians and there is an urgent need for a convenient, instantaneous and accurate road-side evaluation technology for impaired driving. Current solution for roadside drug testing includes a device that is still just a qualitative indicator. Quantitative detection of drugs currently require expensive equipment, […]

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Evaluation of voclosporin treatment as a podocyte-sparing therapy in proteinuric kidney disease

Proteinuric kidney diseases, such as lupus nephritis, affect approximately 1 in 10 individuals around the world. For many patients, it results in the progression to end-stage kidney disease, for which the only treatments available are dialysis and transplantation. Therefore, it is imperative to develop therapies that slow down or halt the progression of proteinuric kidney […]

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Framework Creation of Compensation Strategies in the Social Enterprise Sector

The objective of this research aims to create a framework of compensation strategy that is applicable to the social enterprise sector and create stronger understanding between actual compensations practice and media perception. Therefore, the focus of this study is to gain a stronger understanding of the social enterprise sector (particularly compensation), and the media perceptions […]

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Developing novel varieties of canola, rice and alfalfa with improved cell wall characteristics

Biobased products, mostly derived from plant biomass, have the potential to improve the sustainability of Canada’s natural resources and environmental quality while competing economically. Plant biomass, composed primarily of cell walls and modification of cell wall properties has the potential to improve biomass conversion to biobased products such as biofuels as well as improve feedstock […]

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The design and fabrication of a novel mitral heart valve for catheter-based insertion

The aim of this collaboration is to produce a novel design of percutaneous mitral valve that utilizes the synthetic cryogel material developed at the Heart Valve Performance Laboratory, UBC Okanagan campus for the valve leaflets, along with different anchoring mechanisms to develop an optimized option for testing. The proposed design will be made for either […]

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Development and Optimization of Advanced High-Throughput Behavioural Testing Platforms for the Screening of Mouse Models of Schizophrenia

Operant chambers equipped with touchscreens are a new technology that has been used for the mass behavioural phenotyping of rodent models of neurological disease. These chambers have the potential to make behavioural testing more reliable, faster, and translationally valid to human cognitive testing. To further increase the utility of these systems, technology capable of tracking […]

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Photoacoustic remote sensing microscopy for pre-clinical and clinical applications

There is a desperate need for a fast, non-contact, non-invasive, safe and accurate technique that can measure oxygen saturation, oxygen metabolic activity and multilayered histology-like information. Oxygen saturation and oxygen metabolic activity play a vital role in understanding several diseases including early tumour and vision loss diagnosis and treatment. Additionally, when the oncologic care team […]

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