Targeting CD36 cell surface receptor to treat macrophage-induced chronic inflammation

Chronic inflammation is the common denominator for various diseases, including atherosclerosis, age-related macular degeneration (AMD), obesity, type-2 diabetes, liver diseases and even cancers. In most cases, this inflammation is the result of massive pro-inflammatory macrophage infiltration in tissues, due to their aberrant signalling and dysfunction, in presence of fat accumulation. The CD36 scavenger receptor has […]

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Consumption of Smartphone Application Traffic Markings

Mobile Network Carriers are experiencing data traffic at such high levels that congestion is becoming an increasing problem. High levels of malicious traffic generated from smartphones could potentially bring down the carriers network. As such, mobile carriers are exploring new methods to reduce this congestion. This research focuses on simplifying the problem of identifying which […]

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Resource Allocation for Cloud-Based Notary Service

Cloud computing has emerged as an important platform for business and companies, providing a cost-effective way to scale business service with users’ demand. The proposed research project aims to take full advantage of cloud computing for legal-service companies in Canada, with a particular focus on cloud resource allocation. Unlike conventional resource-allocation schemes that are either […]

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Development of a numerical wave uprush prediction tool for the Cataraqui Region Conservation Authority Lake Ontario and St. Lawrence River shoreline – Phase 2

Wave uprush and the potential for flooding are natural hazards that must be determined by the Cataraqui Region Conservation Authority (CRCA) prior to the approval of a near-shore development. The purpose of calculating wave uprush is to recommend building sites that are outside of the wave uprush area (and floodplain in general) to land owners […]

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Multiphysics Simulation of Optoelectronic Devices, Circuits and Systems

Traditionally, the microchips that power our communications technology use electrical signals to compute, transfer, and store information. Silicon photonics (SiP) is an emerging field, where structures fabricated on those same microchips replace electrical signals with optical ones, enabling exciting new applications such as optical and wireless communications, bio/environment-sensing, and computing. These new optical microchips are […]

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A Healthy Workplace for a Healthy Workforce: Identifying Predictors of Health Impacting Workplace Productivity in the Mining Industry of Saskatchewan

The mining sector plays a huge role in the Saskatchewan economy, in addition to being the largest private sector employer of Aboriginal peoples in the province. It is important economically and socially for the mining workforce to be healthy and productive. Yet we know little about the impacts of physical and mental health on productivity, […]

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Building Information Modeling Enabled Dependency Risk Analysis for Resilient Building Design and Operation

The performance we require from our buildings is ever increasing. Heightened security needs, the push for increasingly efficient use of resources, improved comfort, flexibility of facility space, and changing threats from climate change or other environmental factors are some of the challenges facing designers and operators. There are a complex array of interrelated components that […]

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Feasibility Assessment of the Development of a Cost Effective Type-Specific Small Aircraft Simulator

This project aims to produce a proof-of-concept of a Diamond DA20 aircraft simulator to determine the feasibility of producing the simulator at a low cost while meeting Transport Canada requirements for a minimum of Level 5 Flight Training Device certification. Reducing cost without sacrificing fidelity of the flight simulator comes with many technical challenges which […]

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Outils pour l’aide à la recherche d’information et de veille au CRIQ

Le Centre de recherche industrielle du Québec (CRIQ) offre des services de recherche d’information et de veille en impartition. Actuellement plusieurs outils de recherches sont utilisés pour accomplir ces mandats de recherche d’informations, mais la formulation des requêtes, la sélection des documents pertinents et l’extraction des informations utiles sont effectuées manuellement. Le stage proposé dans […]

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Valorisation de la fibre de lin et de chanvre canadiens pour une nouvelle bio-économie : application au secteur des matériaux bio-composites – Duplicated

Ce projet Mitacs Élévation porte sur le développement des matériaux composites à fibres naturelles (CFN) avec résine bio-sourcée. Notre partenaire, le Centre de Recherche Industriel du Québec (CRIQ), désire développer de nouveaux axes de recherche sur les nouveaux matériaux et/ou procédés. Ils ont déjà un axe orienté sur les matériaux architecturés issus de la fabrication […]

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Utilization of Asparaginase-expressing yeast for the treatment of leukemia

Acute Lymphocytic Leukemia (ALL) is a common form of leukemia that affects approximately 3 people per 100,000 individuals, and is the most common form of cancer in children and adolescents. Current therapies are effective in children, however, treatment success in infants, adolescents, and adults needs improvement. Indeed, there is a need for new chemotherapeutic drugs […]

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