SRRM4 protein purification and antibody production

The SRRM4 gene has been recently identified as a key protein responsible for a subtype of highly aggressive prostate cancers, called neuroendocrine prostate cancer (NEPC). Detection of SRRM4 protein in patient tumor biopsies is therefore important to predict and diagnose NEPC, so that early and more effective therapeutic means can be in place. Unfortunately, there is no SRRM4 antibody currently available that can be used for pathological analyses. This project will join force of academic and industrial expertise to develop a SRRM4 antibody that can be used in clinic for NEPC diagnosis.

Determination of the physicochemical properties of flaxseed oil extractedusing an innovative cold-pressing/filtering system

As one of the healthiest edible oils on the market, flaxseed oil is mostly promoted for its high Omega-3 content.
Regrettably, flaxseed oil is unsuitable for cooking because of its low smoke point. AlliggaTM’s innovative cold pressing/filtering system has remarkably revolutionized this nutritious oil, making it a quality oil to cook with,
while maintaining the richest content of Omega-3 essential fatty acids of any other cooking oil. This project will
determine the frying qualities of Alligga TM flaxseed cooking oil and compare this with other common cooking oils
on the Canadian market.

Advanced design of an inverter for a new application in a telecom dc microgrid

Rapid growth of renewable energy generation and DC loads as electric vehicles and consumer electronics results in the proliferation of DC microgrids. DC microgrids are small electrical grids where energy sources and loads are connected to a main energy distribution power line using power converters.

GIF Tools II – Advanced GeoPhysical Inversion

Over the past 25 years researchers at the UBC Geophysical Inversion Facility (GIF) have generated forward modelling and inversion codes that deal with most types of data of interest to a consortium of mining companies. This proposal moves the research to applications in their corporate environments, and to advance the tools and understanding about how to use the research to date in an efficient manner to extract maximum information from their geophysical data. GIFtools, the computing software for carrying out advanced inversion, was developed for this purpose.

Assessing the Bioactivity of Leech Saliva Extract (LSE) in Combination with Conventional Pharmacological Treatment in Vitro and in Vivo

Medical leeching can be traced back to the beginning of civilization. Ancient Egyptians, Indians, and Greek physicians used leeching as a treatment for a variety of diseases. In the past few decades, comprehensive studies have investigated the therapeutic applications of leech products and especially leech saliva. Recent studies completed by our lab have determined a therapeutic potential of a leech saliva extract component (BPS-001), with demonstrated strong anticancer properties.

Understanding historical forest landscape dynamics in the Alberta foothills

An emerging strategy for managing natural resources such as Canada's forests more sustainably and responsibly is to use knowledge of how Mother Nature has done it to help guide our hand. This so-called ‘ecosystem-based” approach has gained favour with provincial and federal governments, as well as national and international certification agencies.

Environmental productivity patterns of the Salish Sea

Pacific salmon are important from ecological, economic, social and cultural perspectives, but many species in the Salish Sea have seen drastic decrease in marine survival rate in recent decades, likely linked to reduced survival of the young stages of salmon due to a combination of environmental, food web changes, and human impacts. This activity will provide an ecosystem-level analysis of how the environmental productivity of the Salish Sea has changed in recent decades with focus on the implications this has had for salmon populations in the area.

Ecosystem Services and Food Security for the Lil’wat Nation

The Lil’wat Nation is working to foster community food security by restoring and activating Indigenous knowledge around traditional food systems. Our project examines ‘Ecosystem Services’ approaches as one way to support local food security while also protecting culturally-important environmental services. Led by a Lil’wat Food Committee, this project will engage community members in community planning and visioning exercises that evaluate what future paths for environmental stewardship are the highest priority.

Multi-biomarker test for the management of acute cardiac transplant rejection

The high incidence of acute organ rejection following heart transplantation poses major problems for patients, clinicians, and the healthcare system. A major clinical challenge in this regard arises from the difficulty of accurately

Understanding the root causes of record-breaking production

Recently at one of its mines, the partner has experienced a period of unprecedented production. Through its automated production data gathering systems, huge volumes of data are generated on a moment by moment basis at the mine. The goal of this project is to see whether data from this period hold an understanding of the root factors that led to the high production levels and indicate best practices to be implemented on an ongoing basis. This is a big data analytics project. The project will involve applying data and advanced business analytics approaches to analyze the mine’s production data.

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